You’re using a public version of DrugPatentWatch with 5 free searches available | Register to unlock more free searches. CREATE FREE ACCOUNT

Last Updated: April 26, 2024

Claims for Patent: 4,724,144

✉ Email this page to a colleague

« Back to Dashboard

Summary for Patent: 4,724,144

Title:	Immuno-therapeutic composition of killed cells from mycobacterium vaccae
Abstract:	\"Immuno-therapeutic agents of killed cells prepared from Mycobacterium Vaccae that are useful in the treatment of mycobacterial disease, especially tuberculosis or leprosy, in particular as an adjuvant to chemotherapy\".
Inventor(s):	Rook; Graham A. W. (London, GB2), Stanford; John L. (Marden, GB2)
Assignee:	University College London (London, GB2)
Application Number:	06/791,143
Patent Claims:	1. An immunotherapeutic agent consisting essentially of killed cells of Mycobacterium vaccae. 2. An immunotherapeutic agent according to claim 1 comprising cells of M. vaccae which have been killed by irradiation. 3. An immunotherapeutic agent according to claim 1 in sterile injectable liquid form or in sterile freeze-dried form. 4. An immunotherpeutic agent according to claim 1 derived from M. vaccae NCTC 11659. 5. An immunotherapeutic agent according to claim 1 in the form of a single dosage unit containing 10.sup.7 to 10.sup.10 killed cells of M. vaccae. 6. An immunotherapeutic agent according to claim 1 which also comprises BCG vaccine. 7. An immunotherapeutic agent according claim 5 which also comprises BCG vaccine. 8. An immunotherapeutic agent according to claim 1 which also comprises one or more additional ingredients selected from adjuvants, preservatives, and stabilizers. 9. Method of treating mycobacterial disease which comprises administering to a subject suffering therefrom, in association with chemotherapy, killed cells of Mycobacterium vaccae in an amount sufficient to provoke an immune response effective against mycobacteria that survive the chemotherapy. 10. Method according to claim 9 in which the mycobacterial disease is tuberculosis or leprosy and the mycobacteria are Mycobacterium tuberculosis or M. leprae respectively. 11. Method according to claim 9 in which the antigenic material comprises cells of M. vaccae NCTC11659 which have been killed by irradiation.

Details for Patent 4,724,144

Glossary

Subscribe to access the full database, or Try a Trial
Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Teknika Llc	N/A	bcg vaccine	For Injection	103050	06/21/1989	⤷ Try a Trial	2005-02-09
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.