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Last Updated: November 30, 2020

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Claims for Patent: 4,486,403

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Summary for Patent: 4,486,403
Title: Composition for and treatment of teeth
Abstract:The invention relates to compositions and treatments for inhibiting or eliminating the formation of dental caries. The composition comprises a dental carie inhibiting effective amount of a compound containing a thiol group or a disulfide group which compound acts as a collagenase inhibitor and a pharmaceutically acceptable carrier adapted to be applied to and maintained in contact with the teeth. In accordance with the invention this composition is applied to the teeth, the collagenase inhibitor acting to inhibit or even eliminate the formation of dental caries.
Inventor(s): Mechanic; Gerald (Chapel Hill, NC), Binderman; Itzhak (Tel-Aviv, IL)
Application Number:06/450,926
Patent Claims:1. Method for the inhibition or elimination of the formation of dental caries, which comprises the steps of

applying to the teeth to be treated, a collagenase-inhibiting effective amount essentially of cysteine in free form or in the form of a pharmaceutically acceptable salt or complex, and

allowing said collagenase-inhibiting effective amount of cysteine to contact the teeth for a time sufficient to act on the teeth and inhibit the action of collagenase, thereby preventing the formation of dental caries.

Summary for Patent:   Start Trial

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Israel64700Jan 01, 1982

Details for Patent 4,486,403

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial 2002-01-01 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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