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Last Updated: May 8, 2024

Claims for Patent: 4,486,403

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Summary for Patent: 4,486,403

Title:	Composition for and treatment of teeth
Abstract:	The invention relates to compositions and treatments for inhibiting or eliminating the formation of dental caries. The composition comprises a dental carie inhibiting effective amount of a compound containing a thiol group or a disulfide group which compound acts as a collagenase inhibitor and a pharmaceutically acceptable carrier adapted to be applied to and maintained in contact with the teeth. In accordance with the invention this composition is applied to the teeth, the collagenase inhibitor acting to inhibit or even eliminate the formation of dental caries.
Inventor(s):	Mechanic; Gerald (Chapel Hill, NC), Binderman; Itzhak (Tel-Aviv, IL)
Assignee:
Application Number:	06/450,926
Patent Claims:	1. Method for the inhibition or elimination of the formation of dental caries, which comprises the steps of applying to the teeth to be treated, a collagenase-inhibiting effective amount essentially of cysteine in free form or in the form of a pharmaceutically acceptable salt or complex, and allowing said collagenase-inhibiting effective amount of cysteine to contact the teeth for a time sufficient to act on the teeth and inhibit the action of collagenase, thereby preventing the formation of dental caries.

Details for Patent 4,486,403

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Smith & Nephew, Inc.	SANTYL	collagenase	Ointment	101995	06/04/1965	⤷ Try a Trial	2002-01-01
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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