Claims for Patent: 11,286,289

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Summary for Patent: 11,286,289

Title:	T cell receptors
Abstract:	The present invention relates to T cell receptors (TCRs) which bind the HLA-A*0201 restricted peptide GVYDGREHTV (SEQ ID NO: 1) derived from the MAGE-A4 protein. The TCRs of the invention demonstrate excellent specificity profiles for this MAGE epitope. Also provided are nucleic acids encoding the TCRs, cells engineered to present the TCRs, cells harbouring expression vectors encoding the TCRs and pharmaceutical compositions comprising the TCRs, nucleic acids or cells of the invention.
Inventor(s):	Nicholas Tribble, William Lawrance, Eleanor Bagg
Assignee:	Adaptimmune Ltd
Application Number:	US16/154,192

Details for Patent 11,286,289

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Valeant Pharmaceuticals Luxembourg S.à.r.l.	SILIQ	brodalumab	Injection	761032	February 15, 2017	⤷ Start Trial	2038-10-08
Emd Serono, Inc.	BAVENCIO	avelumab	Injection	761049	March 23, 2017	⤷ Start Trial	2038-10-08
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 11,286,289

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Country	Patent Number	Estimated Expiration
Australia	2017248122	⤷ Start Trial
Australia	2022256177	⤷ Start Trial
Brazil	112018070625	⤷ Start Trial
Canada	3020058	⤷ Start Trial
China	109476725	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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