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Last Updated: March 27, 2026

Claims for Patent: 11,147,864

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Summary for Patent: 11,147,864

Title:	Multivalent pneumococcal polysaccharide-protein conjugate composition
Abstract:	Provided are mixed carrier, multivalent pneumococcal conjugate compositions comprising 21 different pneumococcal capsular polysaccharide-protein conjugates, wherein each of the conjugates includes a capsular polysaccharide from a different serotype of Streptococcus pneumoniae conjugated to either tetanus toxoid (TT) or CRM197, wherein the Streptococcus pneumoniae serotypes are selected from 1, 3, 4, 5, 6A, 6B, 7F, 8, 9N, 9V, 10A, 11 A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F, where the capsular polysaccharides of serotypes two of serotypes 1, 3, and 5 are conjugated to TT and the remaining capsular polysaccharides are conjugated to CRM197. Also provided are methods of producing the mixed carrier, multivalent pneumococcal conjugate compositions and methods of using the same for prophylaxis against Streptococcus pneumoniae infection or disease in a subject.
Inventor(s):	Kyungjun AN, Dongsoo HAM, Hun Kim, Sunghyun Kim, Jinhwan SHIN, Robert Hopfer, Richard D. KENSINGER, Moe KYAW, Philippe Talaga
Assignee:	SK Bioscience Co Ltd , Sanofi Pasteur Inc
Application Number:	US16/966,552

Details for Patent 11,147,864

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Wyeth Pharmaceuticals Llc	PREVNAR 13	pneumococcal 13-valent conjugate vaccine (diphtheria crm197 protein)	Injection	125324	February 24, 2010	⤷ Start Trial	2039-02-04
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 11,147,864

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Country	Patent Number	Estimated Expiration
South Africa	202202600	⤷ Start Trial
World Intellectual Property Organization (WIPO)	2019203599	⤷ Start Trial
World Intellectual Property Organization (WIPO)	2019152925	⤷ Start Trial
World Intellectual Property Organization (WIPO)	2019152921	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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