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Last Updated: April 14, 2026

Claims for Patent: 11,045,460

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Summary for Patent: 11,045,460

Title:	Use of Hsp70 as a regulator of enzymatic activity
Abstract:	The present invention concerns a method for modulating the enzymatic activity of an enzyme, wherein said enzyme interacts with BMP, said method comprising the step of administering or inducing Hsp70, or a functional fragment or variant thereof, in a form suitable for allowing interaction between BMP and Hsp70, or said functional fragment or variant thereof, and thereby modulating the enzymatic activity of an enzyme interacting with BMP.
Inventor(s):	Jensen Thomas Kirkegaard, Jaattela Marja H.
Assignee:	Orphazyme A/S
Application Number:	US16698092
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 11,045,460
Patent Claims:

Details for Patent 11,045,460

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Genzyme Corporation	CEREZYME	imiglucerase	For Injection	020367	May 23, 1994	11,045,460	2039-11-27
Genzyme Corporation	CEREZYME	imiglucerase	For Injection	020367	September 22, 1999	11,045,460	2039-11-27
Genzyme Corporation	FABRAZYME	agalsidase beta	For Injection	103979	April 24, 2003	11,045,460	2039-11-27
Genzyme Corporation	FABRAZYME	agalsidase beta	For Injection	103979	October 10, 2003	11,045,460	2039-11-27
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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