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Last Updated: March 26, 2026

Claims for Patent: 10,982,003


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Summary for Patent: 10,982,003
Title:Production of proteins in glutamine-free cell culture media
Abstract:The present invention relates generally to glutamine-free cell culture media supplemented with asparagine. The invention further concerns the production of recombinant proteins, such as antibodies, in asparagine-supplemented glutamine-free mammalian cell culture.
Inventor(s):Martin Gawlitzek, Shun Luo, Christina Teresa Bevilacqua
Assignee:Genentech Inc
Application Number:US16/412,791
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 10,982,003
Patent Claims:

Details for Patent 10,982,003

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. RITUXAN rituximab Injection 103705 November 26, 1997 ⤷  Start Trial 2039-05-15
Idec Pharmaceuticals Corp. RITUXAN rituximab Injection 103737 February 19, 2002 ⤷  Start Trial 2039-05-15
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 September 25, 1998 ⤷  Start Trial 2039-05-15
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 February 10, 2017 ⤷  Start Trial 2039-05-15
Genentech, Inc. AVASTIN bevacizumab Injection 125085 February 26, 2004 ⤷  Start Trial 2039-05-15
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

International Patent Family for US Patent 10,982,003

Country Patent Number Estimated Expiration
South Africa 201200763 ⤷  Start Trial
World Intellectual Property Organization (WIPO) 2011019619 ⤷  Start Trial
United States of America 9714293 ⤷  Start Trial
United States of America 8512983 ⤷  Start Trial
United States of America 2025136705 ⤷  Start Trial
United States of America 2025066493 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration

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