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Last Updated: December 31, 2025

Claims for Patent: 10,934,363

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Summary for Patent: 10,934,363

Title:	Chimeric antigen receptors based on single domain antibodies and methods of use thereof
Abstract:	The present application provides single-domain antibodies, and chimeric antigen receptors comprising one or more antigen binding domains each comprising a single-domain antibody. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating cancer are also provided.
Inventor(s):	Xiaohu Fan, Chuan-Chu Chou, Qiuchuan ZHUANG, Pingyan WANG, Lin Wang, Lei Yang, Jiaying HAO
Assignee:	Legend Biotech USA Inc
Application Number:	US15/751,609

Details for Patent 10,934,363

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Janssen Biotech, Inc.	CARVYKTI	ciltacabtagene autoleucel	For Injection	125746	February 28, 2022	10,934,363	2036-08-10
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,934,363

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Country	Patent Number	Estimated Expiration
South Africa	201807836	⤷ Get Started Free
South Africa	201800703	⤷ Get Started Free
World Intellectual Property Organization (WIPO)	2018028647	⤷ Get Started Free
World Intellectual Property Organization (WIPO)	2017025038	⤷ Get Started Free
United States of America	2024409654	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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