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Last Updated: March 26, 2026

Claims for Patent: 10,906,934


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Summary for Patent: 10,906,934
Title:Protein purification methods
Abstract:The invention provides methods of reducing fouling of ultrafiltration membranes in processes wherein virus particles are removed from aqueous solutions comprising virus particles and at least one protein by adding a surfactant or non-surfactant, non-ionic agent to the aqueous solution prior to filtration. The invention also provides methods to dissociate protein aggregates or to reduce the formation of protein aggregates by adding a surfactant or non-surfactant, non-ionic agent to the protein solution.
Inventor(s):Brown Arick, Ji Junyan, Liu Jun, Wang Yuchang John
Assignee:GENENTECH, INC.
Application Number:US14007610

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