Claims for Patent: 10,668,167

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Summary for Patent: 10,668,167

Title:	Glucocorticoid receptor agonist and immunoconjugates thereof
Abstract:	Provided herein are glucocorticoid receptor agonist immunoconjugates, glucocorticoid receptor agonists, and methods of using the same, e.g., to treat autoimmune or inflammatory diseases.
Inventor(s):	McPherson; Michael J. (Ashby, MA), Hobson; Adrian D. (Shrewsbury, MA), Hayes; Martin E. (Pepperell, MA), Marvin; Christopher C. (Grayslake, IL), Schmidt; Diana (Antioch, IL), Waegell; Wendy (Brookfield, MA), Goess; Christian (Sturbridge, MA), Oh; Jason Z. (Worcester, MA), Hernandez, Jr.; Axel (Charlton, MA), Randolph; John T. (Libertyville, IL)
Assignee:	AbbVie Inc. (North Chicago, IL)
Application Number:	16/408,602
Patent Claims:	1. A compound of the formula ##STR01071## wherein n is 4, and A is an IgG1 antibody comprising a heavy chain comprising the amino acid sequence of SEQ ID NO: 66 and a light chain comprising the amino acid sequence of SEQ ID NO:73. 2. A compound of the formula ##STR01072## wherein n is 2, and A is an IgG1 antibody comprising a heavy chain comprising the amino acid sequence of SEQ ID NO: 66 and a light chain comprising the amino acid sequence of SEQ ID NO:73. 3. A compound of the formula ##STR01073## wherein n is 4, and A is adalimumab. 4. A compound of the formula ##STR01074## wherein n is 2, and A is adalimumab.

Details for Patent 10,668,167

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	December 31, 2002	10,668,167	2039-05-10
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	February 21, 2008	10,668,167	2039-05-10
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	April 24, 2013	10,668,167	2039-05-10
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	September 23, 2014	10,668,167	2039-05-10
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	November 23, 2015	10,668,167	2039-05-10
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	March 09, 2016	10,668,167	2039-05-10
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	October 17, 2016	10,668,167	2039-05-10
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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