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Last Updated: December 30, 2025

Claims for Patent: 10,655,156

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Summary for Patent: 10,655,156

Title:	Overexpression of N-glycosylation pathway regulators to modulate glycosylation of recombinant proteins
Abstract:	Methods of modulating the properties of a cell culture expressing a protein of interest are provided. In various embodiments the methods relate to the overexpression of proteins involved in the N-glycosylation pathway.
Inventor(s):	Shivani Gupta, Sohye Kang
Assignee:	Amgen Inc
Application Number:	US16/261,311

Details for Patent 10,655,156

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Amgen Inc.	PROLIA	denosumab	Injection	125320	June 01, 2010	⤷ Get Started Free	2039-01-29
Amgen Inc.	XGEVA	denosumab	Injection	125320	November 18, 2010	⤷ Get Started Free	2039-01-29
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,655,156

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2015116315	⤷ Get Started Free
United States of America	2020277642	⤷ Get Started Free
United States of America	2019153496	⤷ Get Started Free
United States of America	2019010532	⤷ Get Started Free
United States of America	2017166942	⤷ Get Started Free
United States of America	10907186	⤷ Get Started Free
United States of America	10227627	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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