Last Updated: June 10, 2026

Claims for Patent: 10,376,571

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Summary for Patent: 10,376,571

Title:	Compositions and methods of enhancing immune responses to enteric pathogens
Abstract:	Vaccine vectors capable of eliciting an immune response to enteric bacteria and methods of using the same are provided. The vaccine vectors include a polynucleotide encoding a PAL polypeptide. The PAL polypeptide may be expressed on the surface of the vaccine vector. The vaccine vector may also include a second polypeptide encoding an immunostimulatory polypeptide such as a CD154 polypeptide or an HMGB1 polypeptide.
Inventor(s):	Lisa Bielke, Sherryll Layton, Billy Hargis, Neil R. Pumford, Olivia B. Faulkner, Luc Berghman, Daad ABI-GHANEM
Assignee:	Texas A&M University , University of Arkansas at Little Rock
Application Number:	US14/776,986

Details for Patent 10,376,571

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Csl Behring Llc	ZEMAIRA	alpha-1-proteinase inhibitor (human)	For Injection	125078	July 08, 2003	10,376,571	2034-03-14
Csl Behring Llc	ZEMAIRA	alpha-1-proteinase inhibitor (human)	For Injection	125078	April 16, 2019	10,376,571	2034-03-14
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,376,571

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Country	Patent Number	Estimated Expiration
Argentina	095313	⤷ Start Trial
Australia	2014239557	⤷ Start Trial
Brazil	112015023024	⤷ Start Trial
Canada	2906079	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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