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Last Updated: April 26, 2024

Claims for Patent: 10,188,730

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Summary for Patent: 10,188,730

Title:	Anti-LAG3 antibodies and antigen-binding fragments
Abstract:	The present invention includes antibodies and antigen-binding fragments thereof that specifically bind to human or cynomolgous monkey LAGS as well as immunoglobulin chains thereof and polynucleotides encoding the same along with injection devices comprising such antibodies or fragments. Vaccines including such antibodies and fragments as well as compositions comprising the antibodies and fragments (e.g., including anti-PD1 antibodies) are included in the invention. Methods for treating or preventing cancer or infection using such compositions are also provided. In addition, methods for recombinant expression of the antibodies and fragments are part of the present invention.
Inventor(s):	Liang; Linda (Mountain View, CA), Fayadat-Dilman; Laurence (Sunnyvale, CA), De Waal Malefyt; Rene (Sunnyvale, CA), Raghunathan; Gopalan (San Diego, CA)
Assignee:	Merck Sharp & Dohme Corp. (Rahway, NJ)
Application Number:	15/482,355

Details for Patent 10,188,730

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Merck Sharp & Dohme Corp.	KEYTRUDA	pembrolizumab	For Injection	125514	09/04/2014	⤷ Try a Trial	2034-08-19
Merck Sharp & Dohme Corp.	KEYTRUDA	pembrolizumab	Injection	125514	01/15/2015	⤷ Try a Trial	2034-08-19
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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