Claims for Patent: 10,137,175
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Summary for Patent: 10,137,175
| Title: | Antimicrobial agents |
| Abstract: | The application relates to antimicrobial agents against Gram-negative bacteria, in particular to fusion proteins composed of an enzyme having the activity of degrading the cell wall of Gram-negative bacteria and a peptide stretch fused to the enzyme at the N- or C-terminus, as well as pharmaceutical compositions comprising the same. Moreover, it relates to nucleic acid molecules encoding such a fusion protein, vectors comprising said nucleic acid molecules and host cells comprising either said nucleic acid molecules or said vectors. In addition, it relates to such a fusion protein for use as a medicament, in particular for the treatment or prevention of Gram-negative bacterial infections, as diagnostic means or as cosmetic substance. The application also relates to the treatment or prevention of Gram-negative bacterial contamination of foodstuff, of food processing equipment, of food processing plants, of surfaces coming into contact with foodstuff, of medical devices, of surfaces in hospitals and surgeries. |
| Inventor(s): | Rob Lavigne, Stefan Miller, Yves Briers, Guido Volckaert, Maarten Walmagh |
| Assignee: | Katholieke Universiteit Leuven , Lysando AG |
| Application Number: | US14/535,457 |
Details for Patent 10,137,175
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Sanofi-aventis U.s. Llc | ADLYXIN | lixisenatide | Injection | 208471 | July 27, 2016 | 10,137,175 | 2034-11-07 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
International Patent Family for US Patent 10,137,175
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| World Intellectual Property Organization (WIPO) | 2010149792 | ⤷ Start Trial |
| United States of America | 8906365 | ⤷ Start Trial |
| United States of America | 2019209663 | ⤷ Start Trial |
| United States of America | 2015118731 | ⤷ Start Trial |
| United States of America | 2012189606 | ⤷ Start Trial |
| United States of America | 11052137 | ⤷ Start Trial |
| >Country | >Patent Number | >Estimated Expiration |
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