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Last Updated: March 26, 2026

Claims for Patent: 10,137,175


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Summary for Patent: 10,137,175
Title:Antimicrobial agents
Abstract:The application relates to antimicrobial agents against Gram-negative bacteria, in particular to fusion proteins composed of an enzyme having the activity of degrading the cell wall of Gram-negative bacteria and a peptide stretch fused to the enzyme at the N- or C-terminus, as well as pharmaceutical compositions comprising the same. Moreover, it relates to nucleic acid molecules encoding such a fusion protein, vectors comprising said nucleic acid molecules and host cells comprising either said nucleic acid molecules or said vectors. In addition, it relates to such a fusion protein for use as a medicament, in particular for the treatment or prevention of Gram-negative bacterial infections, as diagnostic means or as cosmetic substance. The application also relates to the treatment or prevention of Gram-negative bacterial contamination of foodstuff, of food processing equipment, of food processing plants, of surfaces coming into contact with foodstuff, of medical devices, of surfaces in hospitals and surgeries.
Inventor(s):Rob Lavigne, Stefan Miller, Yves Briers, Guido Volckaert, Maarten Walmagh
Assignee: Katholieke Universiteit Leuven , Lysando AG
Application Number:US14/535,457

International Patent Family for US Patent 10,137,175

Country Patent Number Estimated Expiration
World Intellectual Property Organization (WIPO) 2010149792 ⤷  Start Trial
United States of America 8906365 ⤷  Start Trial
United States of America 2019209663 ⤷  Start Trial
United States of America 2015118731 ⤷  Start Trial
United States of America 2012189606 ⤷  Start Trial
United States of America 11052137 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration

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