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Last Updated: April 2, 2026

Claims for Patent: 10,098,950

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Summary for Patent: 10,098,950

Title:	PD-1 Peptide Inhibitors
Abstract:	This disclosure provides peptides which have a strong affinity for the checkpoint receptor “programmed death 1” (PD-1). These peptides block the interaction of PD-1 with its ligand PD-L1 and can therefore be used for various therapeutic purposes, such as inhibiting the progression of a hyperproliferative disorder, including cancer, treating infectious diseases, enhancing a response to vaccination, and treating sepsis.
Inventor(s):	Gabriel M. Gutierrez, Vinayaka Kotraiah, James Pannucci, Ramses Ayala
Assignee:	Leidos Inc
Application Number:	US15/705,333

Details for Patent 10,098,950

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Csl Behring Llc	ZEMAIRA	alpha-1-proteinase inhibitor (human)	For Injection	125078	July 08, 2003	10,098,950	2037-09-15
Csl Behring Llc	ZEMAIRA	alpha-1-proteinase inhibitor (human)	For Injection	125078	April 16, 2019	10,098,950	2037-09-15
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,098,950

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Country	Patent Number	Estimated Expiration
Australia	2017325866	⤷ Start Trial
Australia	2018410849	⤷ Start Trial
Canada	3036251	⤷ Start Trial
Canada	3091414	⤷ Start Trial
Denmark	3512536	⤷ Start Trial
Denmark	3758732	⤷ Start Trial
Denmark	3795167	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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