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Last Updated: December 28, 2025

Claims for Patent: 10,039,816


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Summary for Patent: 10,039,816
Title:Siderophore-based immunization against gram-negative bacteria
Abstract:The present invention provides novel enterobactin-carrier protein conjugates and salmochelin-carrier protein conjugates, such as compounds of Formula (I), and salts thereof. The present invention also provides compositions, kits, and methods that involve the compounds of Formula (I) and are useful in inducing an immune response, treating a bacterial infection and/or inflammatory bowel disease in a subject, preventing a bacterial infection and/or inflammatory bowel disease in a subject, or inhibiting the growth of or killing a bacterium.
Inventor(s):Elizabeth Marie Nolan, Phoom Chairatana, Manuela Raffatellu, Martina Sassone Corsi, Araceli Perez-Lopez
Assignee: Massachusetts Institute of Technology , University of California San Diego UCSD
Application Number:US14/700,397

Details for Patent 10,039,816

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Novo Nordisk Inc. TRESIBA insulin degludec Injection 203314 September 25, 2015 ⤷  Get Started Free 2035-04-30
Novo Nordisk Inc. TRESIBA insulin degludec Injection 203314 November 21, 2018 ⤷  Get Started Free 2035-04-30
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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