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Last Updated: May 7, 2024

Claims for Patent: 10,035,766

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Summary for Patent: 10,035,766

Title:	Compositions for preventing and/or treating lysosomal storage disorders
Abstract:	The present invention provides novel compositions as well as methods for preventing and/or treating lysosomal storage disorders. In particular, the present invention provides methods for preventing and/or treating Gaucher\'s disease.
Inventor(s):	Boyd; Robert (Horsham, PA), Lee; Gary (West Windsor, NJ), Rybczynski; Philip (Branchburg, NJ)
Assignee:	Amicus Therapeutics, Inc. (Cranbury, NJ)
Application Number:	14/083,634
Patent Claims:	1. A method for treating type 1 Gaucher's disease in a patient in need of such treatment, which comprises administering to the patient an effective amount of a compound of Formula III: ##STR00035## wherein: R.sup.1 is C(R.sup.2)(R.sup.3)(R.sup.4); R.sup.2 is hydrogen or fluorine; R.sup.3 is fluorine; R.sup.4 is fluorine, C.sub.1-4 alkyl, or phenyl; R.sup.7 is --OH; and R.sup.8 is hydrogen. 2. The method of claim 1, further comprising administering an effective amount of at least one other therapeutic agent. 3. The method of claim 2, wherein the at least one other therapeutic agent is imiglucerase or 1,5-(butylimino)-1,5-dideoxy-D-glucitol. 4. The method of claim 1, wherein R.sup.2 is hydrogen. 5. The method of claim 1, wherein R.sup.2 is fluorine. 6. The method of claim 1, wherein R.sup.4 is fluorine. 7. The method of claim 1, wherein R.sup.4 is C.sub.1-4 alkyl. 8. The method of claim 1, wherein R.sup.4 is phenyl.

Details for Patent 10,035,766

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Genzyme Corporation	CEREZYME	imiglucerase	For Injection	020367	05/23/1994	⤷ Try a Trial	2029-10-19
Genzyme Corporation	CEREZYME	imiglucerase	For Injection	020367	09/22/1999	⤷ Try a Trial	2029-10-19
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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