Last Updated: September 25, 2026

Biologic Drugs With Established Pharmaceutical Class: Uric Acid-specific Enzyme

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Biologic Drugs With Established Pharmaceutical Class: Uric Acid-specific Enzyme

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Patent Expiration
Horizon Therapeutics Ireland Dac	KRYSTEXXA	pegloticase	Injection	125293	2010-09-14	⤷ Start Trial	⤷ Start Trial
Horizon Therapeutics Ireland Dac	KRYSTEXXA	pegloticase	Injection	125293	2010-09-14	10,139,399	⤷ Start Trial
Horizon Therapeutics Ireland Dac	KRYSTEXXA	pegloticase	Injection	125293	2010-09-14	12,188,927	⤷ Start Trial
Horizon Therapeutics Ireland Dac	KRYSTEXXA	pegloticase	Injection	125293	2010-09-14	6,783,965	⤷ Start Trial
Horizon Therapeutics Ireland Dac	KRYSTEXXA	pegloticase	Injection	125293	2010-09-14	9,885,024	⤷ Start Trial
Horizon Therapeutics Ireland Dac	KRYSTEXXA	pegloticase	Injection	125293	2010-09-14	1,013,939,910,139,399	⤷ Start Trial
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Patent Expiration

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