Last Updated: May 10, 2026

Biologic Drugs With Established Pharmaceutical Class: Integrin Receptor Antagonist

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Biologic Drugs With Established Pharmaceutical Class: Integrin Receptor Antagonist

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Patent Expiration
Biogen Inc.	TYSABRI	natalizumab	Injection	125104	2004-11-23	⤷ Start Trial	⤷ Start Trial
Biogen Inc.	TYSABRI	natalizumab	Injection	125104	2004-11-23	5,168,062	⤷ Start Trial
Biogen Inc.	TYSABRI	natalizumab	Injection	125104	2004-11-23	5,385,839	⤷ Start Trial
Biogen Inc.	TYSABRI	natalizumab	Injection	125104	2004-11-23	5,730,978	⤷ Start Trial
Biogen Inc.	TYSABRI	natalizumab	Injection	125104	2004-11-23	5,840,299	⤷ Start Trial
Biogen Inc.	TYSABRI	natalizumab	Injection	125104	2004-11-23	6,033,665	⤷ Start Trial
Biogen Inc.	TYSABRI	natalizumab	Injection	125104	2004-11-23	6,602,503	⤷ Start Trial
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Patent Expiration

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