Patent: 6,033,665

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Summary for Patent: 6,033,665

Title:	Compositions and methods for modulating leukocyte adhesion to brain endothelial cells
Abstract:	The invention is directed to compositions and methods for modulating the adhesion of leukocytes to brain endothelial cells. More specifically, the present invention relates to the use of reagents to inhibit the binding of VLA-4 leukocyte cell surface receptors to brain endothelial adhesion molecules. Also provided are compositions and methods for treating brain inflammation. A method of inducing brain inflammation as well as an assay for testing anti-inflammatory agents is also provided.
Inventor(s):	Yednock; Theodore A. (Fairfax, CA)
Assignee:	Elan Pharmaceuticals, Inc. (South San Francisco, CA)
Application Number:	08/457,847
Patent Claims:	see list of patent claims

Details for Patent 6,033,665

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Biogen Inc.	TYSABRI	natalizumab	Injection	125104	11/23/2004	See Plans and Pricing	2017-03-07
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 6,033,665

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	9105038	See Plans and Pricing
United States of America	5260210	See Plans and Pricing
Japan	H05503920	See Plans and Pricing
Japan	3308526	See Plans and Pricing
>Country	>Patent Number	>Estimated Expiration

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