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Last Updated: March 23, 2023

Patent: 6,033,665

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Summary for Patent: 6,033,665
Title: Compositions and methods for modulating leukocyte adhesion to brain endothelial cells
Abstract:The invention is directed to compositions and methods for modulating the adhesion of leukocytes to brain endothelial cells. More specifically, the present invention relates to the use of reagents to inhibit the binding of VLA-4 leukocyte cell surface receptors to brain endothelial adhesion molecules. Also provided are compositions and methods for treating brain inflammation. A method of inducing brain inflammation as well as an assay for testing anti-inflammatory agents is also provided.
Inventor(s): Yednock; Theodore A. (Fairfax, CA)
Assignee: Elan Pharmaceuticals, Inc. (South San Francisco, CA)
Application Number:08/457,847
Patent Claims:see list of patent claims

Details for Patent 6,033,665

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Biogen Inc. TYSABRI natalizumab Injection 125104 11/23/2004 See Plans and Pricing 2017-03-07
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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