Last Updated: June 17, 2026

LOCOID Drug Patent Profile


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DrugPatentWatch® Litigation and Generic Entry Outlook for Locoid

A generic version of LOCOID was approved as hydrocortisone butyrate by TARO PHARM INDS on January 14th, 2004.

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Summary for LOCOID
US Patents:0
Applicants:3
NDAs:8
Paragraph IV (Patent) Challenges for LOCOID
Tradename Dosage Ingredient Strength NDA ANDAs Submitted Submissiondate
LOCOID Lotion hydrocortisone butyrate 0.10% 022076 1 2016-08-31

US Patents and Regulatory Information for LOCOID

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Bausch LOCOID hydrocortisone butyrate CREAM;TOPICAL 018514-001 Mar 31, 1982 AB1 RX Yes Yes ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Yamanouchi LOCOID hydrocortisone butyrate SOLUTION;TOPICAL 019819-001 Sep 15, 1988 DISCN No No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Precision Dermat LOCOID hydrocortisone butyrate OINTMENT;TOPICAL 018652-001 Oct 29, 1982 DISCN Yes No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Precision Dermat LOCOID LIPOCREAM hydrocortisone butyrate CREAM;TOPICAL 020769-001 Sep 8, 1997 AB2 RX Yes Yes ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Yamanouchi LOCOID hydrocortisone butyrate CREAM;TOPICAL 018795-001 Jan 7, 1983 DISCN No No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Investment scenario and fundamentals analysis for LOCOID

Last updated: February 3, 2026

Overview
LOCOID is a topical corticosteroid indicated primarily for inflammatory skin conditions such as eczema, dermatitis, and psoriasis. It is marketed by IFN Pharma as a low-potency corticosteroid formulation, designed for sensitive skin areas and prolonged use.

Market Position and Regulatory Status
LOCOID's core market includes dermatology clinics and over-the-counter consumers in regions where corticosteroid use is well-regulated. Its regulatory approval varies by region; in select countries, it holds registered approval as a Class IV or low-potency corticosteroid, with specific restrictions on duration of use and prescribing guidelines.

Commercial Landscape
The global dermatology market is valued at approximately $22.7 billion as of 2022. Topical corticosteroids account for a significant share, driven by rising skin disorder prevalence and aging populations. The market shows a compound annual growth rate (CAGR) of roughly 4% from 2022 to 2027. LOCOID competes against other low-potency corticosteroids like hydrocortisone and triamcinolone.

Key Competitors

  • Hydrocortisone creams (e.g., Cortaid)
  • Triamcinolone acetonide (e.g., Kenalog)
  • Mometasone furoate (e.g., Elocon)

LOCOID claims advantages in tolerability and safety for sensitive skin, aiming at a niche within low-potency corticosteroids.

Financial Performance and Investment Considerations

  • Revenue
    Limited publicly available data. Its revenue depends heavily on regional regulatory approvals and prescribing patterns. In mature markets, sales are steady but face competition from generics.

  • Pricing
    The average retail price for topical corticosteroids ranges from $10 to $30 per tube of 15-30 grams (varies by region). LOCOID's premium positioning could command higher margins where targeting sensitive-skin markets.

  • Market Penetration Strategy
    Focus on pediatric and sensitive skin segments, expanding through dermatologist recommendation and OTC channels.

  • Patent and Intellectual Property
    The patent life for LOCOID formulations is critical. If patent protection lapses or is challenged, generic competition may erode margins. The brand's current patent status needs regular review.

Regulatory and Legal Risks

  • Stringent regulations limit long-term or overuse of corticosteroids.
  • Variability across jurisdictions can complicate expansion.
  • Patent expirations threaten market exclusivity.

R&D and Pipeline

  • Limited information on ongoing pipeline products.
  • If R&D continues, focus may shift toward formulations with improved safety or reduced systemic absorption.

Key Risks

  • Intensifying competition from generic low-potency corticosteroids.
  • Regulatory restrictions lowering prescription volumes.
  • Potential adverse publicity over corticosteroid side effects.

Investment Outlook

  • Positive Factors: steady demand from sensitive skin markets, low-cost manufacturing, and potential for niche expansion.
  • Negative Factors: commoditization, patent cliffs, and regulatory hurdles reduce growth prospects.

Conclusion

  • LOCOID presents a moderate growth opportunity within the dermatology therapeutics sector, primarily dependent on regional regulatory environments and patent protection. Its market share will likely remain stable if it maintains regulatory compliance and develops targeted marketing strategies.

Key Takeaways

  • LOCOID's market relies on the dermatology sector with limited growth margins but stable demand.
  • Competitive pressure from generics and patent expirations are significant risks.
  • Strategic focus on sensitive skin segments could improve market positioning.
  • Regulatory restrictions influence sales volume and geographic expansion.
  • Ongoing patent protection and R&D are critical to sustaining profitability.

FAQs

1. What attributes differentiate LOCOID from other corticosteroids?
LOCOID is marketed as a low-potency corticosteroid suitable for sensitive skin and prolonged use, with a focus on safety profile and minimal side effects.

2. How does patent expiration affect LOCOID’s revenue prospects?
Patent expiration allows generic manufacturers to enter the market, typically reducing prices and market share, which can significantly impact revenue streams.

3. What regulatory challenges might LOCOID face?
Restrictions on corticosteroid duration and use, differing approval standards between countries, and evolving safety guidelines can limit sales or delay expansion.

4. How competitive is the landscape for topical corticosteroids?
Highly competitive with numerous generics offering similar formulations, which limits pricing power and market differentiation.

5. What strategic moves could enhance LOCOID’s market position?
Focusing on niche segments with unmet needs, strengthening patent protections, and expanding into emerging markets with regulatory approval.


References

[1] Global Dermatology Market, MarketWatch, 2022.
[2] Topical Corticosteroids Market, Allied Market Research, 2022.
[3] Regulatory guidelines for corticosteroids, FDA, 2021.

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