Last Updated: September 28, 2026

hydroxyurea - Profile


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What are the generic sources for hydroxyurea and what is the scope of freedom to operate?

Hydroxyurea is the generic ingredient in five branded drugs marketed by Waylis Therap, Barr, Barr Labs Inc, Leading, Ph Health, Qilu, Roxane, Nova Labs Ltd, and Theravia, and is included in ten NDAs. There is one patent protecting this compound. Additional information is available in the individual branded drug profile pages.

There is one tentative approval for this compound.

Summary for hydroxyurea
International Patents:9
US Patents:1
Tradenames:5
Applicants:9
NDAs:10
Generic filers with tentative approvals for HYDROXYUREA
Applicant Application No. Strength Dosage Form
⤷  Start Trial⤷  Start Trial1GMTABLET;ORAL
⤷  Start Trial⤷  Start Trial100MGTABLET;ORAL

The 'tentative' approval signifies that the product meets all FDA standards for marketing, and, but for the patents / regulatory protections, it would approved.

US Patents and Regulatory Information for hydroxyurea

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Waylis Therap DROXIA hydroxyurea CAPSULE;ORAL 016295-002 Feb 25, 1998 RX Yes No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Waylis Therap DROXIA hydroxyurea CAPSULE;ORAL 016295-003 Feb 25, 1998 RX Yes No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Waylis Therap DROXIA hydroxyurea CAPSULE;ORAL 016295-004 Feb 25, 1998 RX Yes No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Waylis Therap HYDREA hydroxyurea CAPSULE;ORAL 016295-001 Approved Prior to Jan 1, 1982 AB RX Yes Yes ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

International Patents for hydroxyurea

Country Patent Number Title Estimated Expiration
Australia 2019269123 A stable aqueous hydroxycarbamide solution ⤷  Start Trial
European Patent Office 3644967 SOLUTION AQUEUSE STABLE D'HYDROXYCARBAMIDE (A STABLE AQUEOUS HYDROXYCARBAMIDE SOLUTION) ⤷  Start Trial
European Patent Office 4434580 SOLUTION AQUEUSE STABLE D'HYDROXYCARBAMIDE (A STABLE AQUEOUS HYDROXYCARBAMIDE SOLUTION) ⤷  Start Trial
Spain 2992016 ⤷  Start Trial
>Country >Patent Number >Title >Estimated Expiration

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