Last Updated: May 3, 2026

cupric sulfate - Profile


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What are the generic sources for cupric sulfate and what is the scope of patent protection?

Cupric sulfate is the generic ingredient in three branded drugs marketed by Abraxis Pharm, Am Regent, and Apotex Corp, and is included in four NDAs. There are five patents protecting this compound. Additional information is available in the individual branded drug profile pages.

Summary for cupric sulfate
US Patents:5
Tradenames:3
Applicants:3
NDAs:4

US Patents and Regulatory Information for cupric sulfate

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Abraxis Pharm CUPRIC SULFATE cupric sulfate INJECTABLE;INJECTION 019350-001 May 5, 1987 DISCN Yes No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Am Regent CUPRIC SULFATE cupric sulfate INJECTABLE;INJECTION 216324-001 Dec 16, 2022 RX No Yes ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Apotex Corp CUPRIC SULFATE cupric sulfate INJECTABLE;INJECTION 218745-001 Aug 19, 2024 DISCN No No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Am Regent MULTRYS cupric sulfate; manganese sulfate; selenious acid; zinc sulfate SOLUTION;INTRAVENOUS 209376-003 Jun 30, 2021 RX Yes Yes 12,150,957 ⤷  Start Trial ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Investment scenario and fundamentals analysis for Cupric Sulfate

Last updated: February 5, 2026


What Is Cupric Sulfate and Why Is It Relevant for Investment?

Cupric sulfate, known chemically as copper(II) sulfate pentahydrate (CuSO4ยท5H2O), is a chemical compound with established uses in agriculture, mining, and industrial processes. While not a pharmaceutical drug, its derivatives and applications have relevance to sectors related to pharmaceutical manufacturing, such as agriculture-driven drug production and pharmaceutical-grade chemical supply chains.

The compound is mainly used in fungicides, algicides, and as a nutritional supplement in animal feed additives. Its role within human or veterinary medicine is primarily as a mineral supplement, and it occasionally appears as an ingredient in topical antimicrobial formulations.

What Are the Market Fundamentals and Growth Drivers?

Market Size and Trends

  • The global copper sulfate market was valued at approximately $600 million in 2022.
  • Compound annual growth rate (CAGR) projected at 3.2% from 2023 to 2030.
  • Growth driven by increasing adoption in agriculture (fungicide and pesticidal applications), and expanding use as a mineral supplement in animal feed.

Key Applications

  • Agriculture: 50% of demand, fungicidal and pesticidal uses.
  • Mining: used in flotation processes for mineral extraction.
  • Industrial: electroplating, textile dyeing, and wood preservation.
  • Pharmaceuticals: limited, primarily as a mineral supplement or in chemical synthesis.

Regulatory Environment

  • Regulatory approval varies by country. In the U.S., the EPA regulates copper-based pesticides, with re-registration occurring periodically based on safety data.
  • Stringent environmental regulations affect discharge and usage, influencing production costs and supply.

Supply Chain Considerations

  • Major producers are China, Chile, and Peru.
  • Copper sulfate production is sensitive to raw material costs, primarily copper prices.
  • Environmental compliance and sustainable mining practices affect manufacturing costs and capacity expansion.

Investment Risks and Challenges

  • Fluctuating copper prices impact profitability.
  • Regulatory changes may restrict or increase compliance costs.
  • Alternative fungicidal and pesticidal agents could reduce demand.
  • Environmental concerns regarding copper runoff and toxicity may restrict future use.

Competitive Landscape

Company Market Position Key Strengths Notes
Zash Global Wellness Leading agrochemical supplier Large production capacity Diversifying into pharmaceutical ingredients
TMC Life Sciences Niche specialty chemicals Strong R&D in mineral applications Potential for pharmaceutical-grade applications
ChemChina (Syngenta) Major agrochemical firm Extensive distribution network Focused on sustainable pesticides

Investment Considerations

  • The industry shows moderate growth with stable demand driven by agriculture and industrial uses.
  • Supply chain dependencies expose valuations to copper price fluctuations.
  • Environmental and regulatory risks may influence long-term profitability.
  • Companies with diversified portfolios or integrated supply chains better positioned.

Key Takeaways

  1. Market size in 2022 was approximately $600 million, with steady growth projected at over 3% annually.
  2. Major demand stems from agriculture, comprising half of total consumption, with industrial and mining sectors providing additional outlets.
  3. Regulatory and environmental factors significantly influence production costs and product viability.
  4. Supply chains are concentrated in South America and China, with copper prices closely linked to profitability.
  5. Risks include price volatility, regulatory restrictions, and potential substitution with alternative chemicals.

FAQs

Q1: Is Cupric Sulfate directly used in pharmaceutical manufacturing?
No, it is not typically a pharmaceutical active ingredient but is used as a mineral supplement and in chemical synthesis that may support pharmaceutical production.

Q2: What are the primary regulatory constraints impacting Cupric Sulfate investments?
Environmental regulations targeting copper runoff, water discharge standards, and pesticide registration processes influence market access and production costs.

Q3: How sensitive is the Cupric Sulfate market to copper prices?
Highly sensitive. Fluctuations in copper prices significantly affect manufacturing costs and margins.

Q4: Are there opportunities in pharmaceutical applications?
Limited. Opportunities exist where pharmaceutical-grade CuSO4 meets stringent purity standards, especially in specialty chemical synthesis.

Q5: Which regions present the most promising growth opportunities?
Asia-Pacific, driven by demand in agriculture and growing industrialization, and South America, owing to raw material availability and established production facilities.


Citations

[1] MarketsandMarkets, "Copper Sulfate Market," 2022.
[2] ResearchAndMarkets, "Global Copper Sulfate Market," 2023.
[3] U.S. EPA, "Pesticide Registration Regulations," 2021.
[4] ICIS, "Copper prices overview," 2023.

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