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2019 — 12 Books and Research Papers Citing DrugPatentWatch
Chaudhuri, S. (2019). Are Medicine Prices High and Unaffordable after TRIPS? Evidence from Pharmaceutical Industry in India. SSRN.
This paper examines the impact of the Trade-Related Aspects of Intellectual Property Rights (TRIPS) agreement on drug prices in India. It uses data from DrugPatentWatch to analyze patenting trends and their correlation with medication affordability. The study finds that while TRIPS compliance led to higher patenting activity, it did not significantly reduce the affordability of medicines in India.
Kendzierskyj, S., & Jahankhani, H. (2019). Healthcare Patient and Clinical Research. In Cybersecurity and Clinical Trial: Securing Patient Data. Springer.
This chapter examines the security and privacy challenges involved in clinical trial data management, particularly as digital systems and cloud storage become more prevalent. The authors emphasize the need for robust data governance models and encryption technologies to protect sensitive patient information. For DrugPatentWatch users, this work underscores the increasing role of cybersecurity in clinical trials—especially relevant when evaluating the data infrastructure of competitors or potential CDMO partners involved in trial management.
Baber, U., Leisman, D. E., Cohen, D. J., et al. (2019). Tailoring Antiplatelet Therapy Intensity to Ischemic and Bleeding Risk: A Cost Consequence Simulation from PARIS. Circulation: Cardiovascular Quality and Outcomes, 12(7), e005985.
This study uses simulation modeling based on the PARIS registry to evaluate the cost-effectiveness of personalized antiplatelet therapy for patients with varying ischemic and bleeding risks. It concludes that tailoring therapy leads to better health outcomes and lower costs. For pharmaceutical strategy and patent watchers, this type of evidence can support value-based pricing arguments and may drive adoption or differentiation of newer antiplatelet drugs with favorable safety profiles.
Bennaghmouch, N., de Veer, A. J. W. M., & others. (2019). Economic evaluation of the use of non-vitamin K oral anticoagulants in patients with atrial fibrillation on antiplatelet therapy: a modelling analysis using the healthcare payer perspective in the Netherlands. European Heart Journal - Quality of Care and Clinical Outcomes, 5(3), 235–243.
This paper provides a cost-utility analysis of using NOACs (non-vitamin K oral anticoagulants) in patients with atrial fibrillation who are also on antiplatelet therapy. The study supports NOACs as a cost-effective alternative in the Dutch healthcare system. Patent strategists and competitive analysts can use such models to evaluate post-patent lifecycle value and pricing strategies, particularly in jurisdictions with strong pharmacoeconomic decision-making systems.
Kulakova, A. V. (2019). Characterization and solution structure of multi-domain proteins and protein complexes. Doctoral Dissertation, Technical University of Denmark (DTU).
This dissertation focuses on advanced structural biology methods used to determine the conformation of multi-domain proteins and their complexes in solution. These findings are vital for rational drug design and understanding protein-ligand interactions. For DrugPatentWatch users tracking biologics or next-gen protein therapies, the methodology can inform assessments of patentable molecular configurations or predictability of biosimilar development hurdles.
Pila, J. (2019). Property in human genetic material: An old legal question for a new technological age. In: Coggon, J., Gola, A., & Sándor, J. (Eds.), The Oxford Handbook of Comparative Health Law. Oxford University Press.
Pila reviews the contentious legal landscape surrounding property rights in human genetic material. The chapter delves into the implications of recognizing ownership or control over genomic sequences, especially in light of CRISPR and gene therapies. For DrugPatentWatch users focused on patent law, this work provides context on evolving legal definitions that could impact patent eligibility and enforceability in the genetic medicine space.
Abad, V. C. (2019). An evaluation of sodium oxybate as a treatment option for narcolepsy. Expert Opinion on Pharmacotherapy, 20(15), 1831–1837.
This article evaluates sodium oxybate's efficacy and safety profile for narcolepsy treatment, noting its superiority in improving sleep architecture and reducing cataplexy episodes. The paper also addresses scheduling and abuse potential, which affect regulatory pathways and market access. For patent and generic strategy professionals, understanding such therapeutic profiles is critical in predicting market exclusivity battles, especially in CNS drug markets with tight risk-benefit scrutiny.
Zheng, W. (2019). Patent Abandonment and Subsequent Cumulative Inventions. CORE.
This paper explores the phenomenon of patent abandonment and its effects on subsequent innovation. By analyzing patent data from DrugPatentWatch, the author examines how the abandonment of patents influences the rate and direction of future inventions in related fields. The study suggests that patent abandonment can lead to increased cumulative innovations, as barriers to entry are reduced.
Choi, S., Lee, H., Park, E. L., & Choi, S. (2019). Deep Patent Landscaping Model Using Transformer and Graph Embedding. arXiv preprint arXiv:1903.05823.
Addressing the need for automated patent landscape analysis, this study deploys a transformer-based text encoder combined with a Diff2Vec graph embedding to capture both textual and metadata features. They also release four benchmark datasets for patent landscaping model comparisons. For DrugPatentWatch, this approach exemplifies how advanced NLP and network embeddings can streamline identification of competitive patents, trending technologies, and white-space opportunities in drug innovation domains.
Fujimoto, J., Tien, D. M., & Snyder, S. (2019). The Effect of Patent Expiration on Sales of Branded Competitor Drugs in a Therapeutic Class. Journal of Generic Medicines, 16(4), 151–160.
This study investigates the sales impact on branded competitor drugs following the patent expiration of a leading drug within the same therapeutic class. Utilizing data from DrugPatentWatch, the authors quantify the market share shifts and revenue changes among competitors post-expiration. The findings indicate that patent expirations lead to significant sales gains for branded competitors, even in the presence of generics.
Основа научных исследований-информационная база
Н Сафронова, Т Нечаева, О Сонных - Наука и инновации, 2019 - cyberleninka.ru
Оптимизация лекарственного обеспечения пациентов со злокачественными новообразованиями на уровне субъекта Российской Федерации
АВ Никитина, ФВ Горкавенко… - Фармакоэкономика …, 2019 - cyberleninka.ru
