Last updated: August 1, 2026
The branded product is manufactured by Baxter Healthcare Corporation and supplied through Baxter’s institutional and dialysis-product distribution network. The exact package size, NDC, and regional availability should be matched before ordering because DIANEAL products are sold in multiple configurations.
Who manufactures DIANEAL Low Calcium With Dextrose 4.25%?
| Product |
Active solution |
Container |
Manufacturer |
Product category |
| DIANEAL Low Calcium With Dextrose 4.25% |
Peritoneal dialysis solution containing 4.25% dextrose |
Plastic container |
Baxter Healthcare Corporation |
Prescription peritoneal dialysis solution |
Baxter is the primary manufacturer and brand owner for DIANEAL peritoneal dialysis solutions. The product is used for peritoneal dialysis and is supplied to dialysis providers, hospitals, specialty pharmacies, and medical-product distributors. [1][2]
Where can buyers source this product?
Primary supplier
Baxter Healthcare Corporation
Baxter supplies DIANEAL products directly to dialysis organizations, hospitals, health systems, and qualified medical distributors. Institutional buyers generally purchase through a Baxter account representative, contracted group-purchasing organization, or authorized distributor.
Major medical-product distribution channels
The product may be procured through large U.S. healthcare distributors, subject to current stock and contract status:
| Distributor |
Typical customer base |
Product availability |
| McKesson Medical-Surgical |
Hospitals, dialysis centers, clinics, pharmacies |
Product-specific inventory and contract status must be confirmed |
| Cardinal Health |
Hospitals, health systems, specialty providers |
Product-specific inventory and contract status must be confirmed |
| Medline |
Hospitals, clinics, home-care providers |
Availability depends on regional distribution and customer account |
| Dialysis-focused medical suppliers |
Dialysis clinics and home dialysis providers |
May source Baxter products through authorized channels |
The most reliable route for recurring supply is a direct Baxter account or an established dialysis-equipment distributor. Retail pharmacy availability is generally less consistent because DIANEAL is a clinical dialysis product rather than a routine outpatient prescription medicine.
What product specifications must be matched?
Purchasers should verify all of the following before substituting or ordering:
- DIANEAL brand and formulation
- Low-calcium formulation
- 4.25% dextrose concentration
- Plastic container
- Container volume
- Single- or dual-compartment configuration
- Calcium and magnesium concentrations
- Sterility and package integrity
- Required delivery system or transfer set
- NDC or local product identifier
- Shipping and storage requirements
DIANEAL solutions are not interchangeable solely because they have the same dextrose concentration. Calcium concentration, buffer system, electrolyte composition, container design, and connection system can differ across products.
What are the available alternatives?
Baxter’s DIANEAL portfolio includes other dextrose concentrations and electrolyte formulations. Alternative peritoneal dialysis solutions are also marketed by other manufacturers, but they should be evaluated against the prescribed formulation and dialysis-system compatibility.
| Manufacturer |
Relevant product family |
Relationship to the requested product |
| Baxter Healthcare |
DIANEAL |
Exact branded product family |
| Fresenius Medical Care |
Stay·Safe and related peritoneal dialysis products |
Potential therapeutic or system alternative, not the same branded product |
| Other regional suppliers |
Country-specific peritoneal dialysis solutions |
Availability and regulatory status vary by jurisdiction |
A competing solution is not an automatic replacement for DIANEAL Low Calcium With Dextrose 4.25%. The prescribing nephrologist and dialysis provider must approve any formulation or system change.
How should U.S. buyers verify the correct product?
For U.S. procurement, buyers should confirm the product through:
- Baxter’s current product catalog or institutional sales channel.
- The FDA National Drug Code Directory, where applicable.
- The product’s official labeling and package insert.
- The purchasing organization’s distributor catalog.
- The dialysis provider’s approved formulary and equipment list.
The exact NDC can vary by package configuration. Buyers should not rely on the product name alone when placing an order. [1][3]
What is the regulatory status of DIANEAL?
DIANEAL is a prescription peritoneal dialysis solution regulated in the United States as a drug product. Its labeling identifies the solution’s dextrose concentration, electrolyte composition, calcium level, indications, warnings, preparation requirements, and administration instructions. [1]
The product is administered in a clinical or home-dialysis setting under the direction of a qualified healthcare professional. Distribution is typically limited to healthcare institutions, dialysis organizations, specialty providers, and medical-product suppliers.
Key Takeaways
- Baxter Healthcare Corporation is the primary manufacturer and branded supplier.
- The product is DIANEAL Low Calcium With Dextrose 4.25% in a plastic container, a peritoneal dialysis solution.
- Institutional buyers can source it through Baxter or major healthcare distributors such as McKesson, Cardinal Health, and Medline, subject to current inventory and account contracts.
- Buyers must verify the container size, NDC, calcium formulation, connection system, and package configuration before ordering.
- Fresenius and other manufacturers may offer peritoneal dialysis alternatives, but their products are not identical substitutes.
FAQs
Can community pharmacies order DIANEAL 4.25%?
Some pharmacies may be able to obtain DIANEAL through a specialty or medical-product distributor, but dialysis centers and home-dialysis providers are the more common procurement channels.
Is DIANEAL Low Calcium 4.25% the same as standard DIANEAL 4.25%?
No. The calcium concentration and electrolyte formulation must be verified. Products with the same dextrose concentration can have different calcium levels and are not automatically interchangeable.
Does Baxter sell DIANEAL directly to patients?
Baxter primarily supplies healthcare institutions, dialysis providers, and authorized distributors. Home patients generally receive product through their dialysis provider or a contracted home-care supplier.
Can Stay·Safe or another Fresenius solution replace DIANEAL?
Only after clinical and equipment compatibility review. Dialysis solutions differ in formulation, packaging, connectors, transfer systems, and prescribing requirements.
What information should appear on a purchase order?
The purchase order should identify the DIANEAL formulation, 4.25% dextrose strength, low-calcium designation, container type, package volume, quantity, NDC or catalog number, and required delivery date.
References
- Baxter Healthcare Corporation. (n.d.). DIANEAL peritoneal dialysis solution prescribing information. Baxter Healthcare Corporation.
- Baxter Healthcare Corporation. (n.d.). Peritoneal dialysis solutions and systems. Baxter Healthcare Corporation.
- U.S. Food and Drug Administration. (n.d.). National Drug Code Directory. FDA.
