Last updated: August 6, 2025
Overview of DELFLEX W/ DEXTROSE 2.5% LOW MAGNESIUM
Delflex, a commercially available intravenous (IV) fluid, is primarily composed of dextrose 2.5% with a low concentration of magnesium. It is a sterile, non-preserved solution supplied in plastic containers, primarily used for hydration, energy supply, and electrolyte replenishment in clinical settings. The formulation and packaging are subject to strict regulatory standards, including adherence to pharmacopoeia specifications (USP, BP, or EP).
Key Components and Specifications
- Active ingredients: Dextrose monohydrate (2.5%), magnesium sulfate (low concentration)
- Container Type: Plastic (typically PVC or polyolefin-based IV bags/container)
- Sterility: Ensured through aseptic manufacturing practices
- Storage Conditions: Usually between 15°C to 30°C, protected from light
- Labeling: Compliant with regulatory standards, indicating batch number, expiry date, and storage instructions
Major Global and Regional Suppliers
The market for IV solutions like Delflex is concentrated among several key manufacturers, predominantly located in regions with advanced pharmaceutical manufacturing infrastructure. The following are some notable suppliers:
1. Baxter International Inc.
Overview: Baxter is a leading supplier of IV solutions worldwide, including dextrose and electrolyte solutions. Their product lines include pre-filled and flexible IV bags with customized electrolyte compositions. Baxter’s solutions are manufactured under rigorous quality standards and distributed globally.
Product Details:
- Variations of dextrose solutions, including 2.5% concentrations
- Magnesium content adjusted per formulation
- Packaging: PVC-based IV bags complying with USP standards
Sources: Baxter’s extensive catalog of IV solutions [1].
2. Pfizer Inc.
Overview: Pfizer manufactures various parenteral nutrition and hydration solutions, including dextrose-based solutions with electrolyte adjustments. Their formulations often include magnesium when indicated clinically.
Product Details:
- Dextrose 2.5% solutions with electrolyte adjustments
- Emphasis on sterile manufacturing and secure plastic containers
Regional Presence: Significant in North America, Europe, and Asia-Pacific.
Sources: Pfizer product literature and regional catalogs [2].
3. B. Braun Melsungen AG
Overview: B. Braun supplies a broad portfolio of infusion solutions, including customized dextrose and electrolyte formulations.
Product Details:
- Dextrose solutions with low magnesium content
- Plastic infusion bags conforming to regulatory specifications
- Emphasis on safety, including various infusion protocols and sterile manufacturing
Sources: B. Braun’s official product range [3].
4. Hospira (a Pfizer company)
Overview: Specializes in sterile injectable and infusion solutions. Known for their comprehensive portfolio in IV fluids.
Product Details:
- Dextrose solutions with electrolyte compositions, including low magnesium variants
- Use of flexible plastic containers designed for compatibility and sterility
Sources: Hospira product specifications [4].
5. Fresenius Kabi
Overview: Focuses on injectable medicines and infusion solutions, including dextrose-based formulations tailored for clinical use.
Product Details:
- Dextrose 2.5% infusion solutions with optional electrolyte adjustments
- Solutions provided in specialized plastic containers ensuring stability
Sources: Fresenius Kabi product datasheets [5].
Regional and Local Suppliers
In addition to global giants, numerous regional manufacturers supply Delflex or equivalent formulations, especially in emerging markets such as Asia, Latin America, and Eastern Europe. These suppliers often cater to local hospitals and clinics, complying with regional pharmaceutical regulations.
Regulatory Considerations
Manufacturers must adhere to stringent quality standards set by agencies like the FDA (U.S.), EMA (Europe), and PMDA (Japan). Suppliers are required to provide comprehensive documentation, including batch consistency, sterility assurance, and stability data.
Emerging Suppliers and Contract Manufacturers
International contract manufacturing organizations (CMOs) also produce fluorinated, dextrose-based solutions for third-party pharmaceutical firms. Notable entities include:
- Siegfried AG
- Dr. Reddy’s Laboratories
- Hainan Topfond Pharmaceutical Co., Ltd.
These CMOs often supply private label products, including Delflex variants, under exact specifications requested by pharma companies.
Supply Chain Dynamics and Trends
- Consolidation & Mergers: Large firms acquiring smaller regional suppliers to ensure quality control and consistent supply.
- Technological Innovations: Development of advanced plastic formulations reducing leaching and maintaining stability.
- Regulatory Harmonization: Increased global standards facilitate cross-border procurement, expanding market access for certified suppliers.
- Sustainability Efforts: Shift toward eco-friendly packaging solutions, including biodegradable plastics, influencing supplier choices.
How to Source Suppliers
For healthcare providers or pharmaceutical companies seeking Delflex W/ DEXTROSE 2.5% LOW MAGNESIUM, sourcing options include:
- Direct procurement: Contacting manufacturer representatives or regional distribution partners.
- Authorized distributors: Ensuring product authenticity and regulatory compliance.
- Tender processes: Participating in regional procurement tenders to secure competitive pricing and supply security.
Key Takeaways
- Market Leaders: Baxter, Pfizer, B. Braun, Hospira, and Fresenius Kabi dominate the supply of dextrose solutions, including Delflex variants.
- Regional Diversity: Multiple regional manufacturers fill local demand, particularly in emerging markets.
- Regulatory Compliance: Confirm supplier adherence to regional and international standards to ensure safety and efficacy.
- Supply Chain Stability: Evaluate the supplier's manufacturing capacity, QC processes, and distribution network.
- Innovative Packaging: Prioritize suppliers adopting advanced, sustainable plastic containers to optimize safety and environmental footprint.
FAQs
1. What are the primary suppliers of Delflex W/ DEXTROSE 2.5% LOW MAGNESIUM?
Major global suppliers include Baxter International, Pfizer, B. Braun, Hospira, and Fresenius Kabi.
2. How can I verify the quality of products from these suppliers?
Verify supplier accreditation, compliance with CE/FDA approvals, and quality certifications such as ISO 13485. Request batch testing reports and Certificate of Analysis (COA).
3. Are there regional suppliers providing similar formulations?
Yes, many regional manufacturers in Asia, Latin America, and Eastern Europe produce Delflex-like products, often tailored to local regulatory standards.
4. What factors influence supplier selection for this product?
Factors include regulatory compliance, product quality, supply stability, pricing, compatibility with existing medical infrastructure, and sustainability initiatives.
5. How does regulatory approval affect procurement?
Only products approved by relevant health authorities (e.g., FDA, EMA) are deemed suitable for clinical use, directly impacting supplier selection and procurement decisions.
References
[1] Baxter International Inc. Product catalog. Baxter.com.
[2] Pfizer Inc. Product information. Pfizer.com.
[3] B. Braun Melsungen AG. Clinical solutions portfolio. Bbraun.com.
[4] Hospira (Pfizer). Intravenous solutions specifications. Hospira.com.
[5] Fresenius Kabi. Infusion collection. Fresenius-kabi.com.
