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Last Updated: April 4, 2026

Suppliers and packagers for generic pharmaceutical drug: SPINOSAD


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SPINOSAD

Listed suppliers include manufacturers, repackagers, relabelers, and private labeling entitities.

Applicant Tradename Generic Name Dosage NDA NDA/ANDA Supplier Package Code Package Marketing Start
Cipher NATROBA spinosad SUSPENSION;TOPICAL 022408 NDA AUTHORIZED GENERIC Allegis Pharmaceuticals, LLC 28595-570-04 1 BOTTLE, PLASTIC in 1 CARTON (28595-570-04) / 120 mL in 1 BOTTLE, PLASTIC 2014-06-25
Cipher NATROBA spinosad SUSPENSION;TOPICAL 022408 NDA AUTHORIZED GENERIC ParaPRO LLC 52246-570-04 1 BOTTLE, PLASTIC in 1 CARTON (52246-570-04) / 120 mL in 1 BOTTLE, PLASTIC 2024-01-29
Cipher NATROBA spinosad SUSPENSION;TOPICAL 022408 NDA ParaPRO LLC 52246-929-04 1 BOTTLE, PLASTIC in 1 CARTON (52246-929-04) / 120 mL in 1 BOTTLE, PLASTIC 2011-01-25
>Applicant >Tradename >Generic Name >Dosage >NDA >NDA/ANDA >Supplier >Package Code >Package >Marketing Start

Suppliers for the Pharmaceutical Drug Spinosad

Last updated: February 20, 2026

Who Are the Leading Suppliers of Spinosad?

Spinosad is a natural insecticide derived from the fermentation of Saccharopolyspora spinosa. It is used primarily in pest control for agricultural and veterinary applications, not as a pharmaceutical, but sometimes it is referenced in formulations for human health or specialized uses. The main commercial suppliers include:

  • Dow AgroSciences (Now Corteva Agriscience)
    Became the primary producer after acquiring Mycogen Seeds, which initially developed spinosad-based products. Their product, Naturalyte, is well known in pest control sectors.

  • Phibro Animal Health
    Markets spinosad for veterinary parasitic control, particularly in flea control products for dogs and cats under brands like Comfortis.

  • Elanco Animal Health
    Manufactures and distributes spinosad-based antiparasitic formulations, especially in veterinary medicine.

  • Koppert Biological Systems
    Provides biopesticides including spinosad formulations tailored for integrated pest management in agriculture.

  • Certis USA
    Sells spinosad for agricultural and residential pest control, marketed under trade names like Entrust.

  • BASF
    Produces spinosad formulations used in crop protection and pest control products.

Geographic Distribution & Market Dynamics

Supplier Regions Covered Product Uses Market Share (Estimate)
Corteva Agriscience Global, North America, Europe Agriculture, commercial pest control >50%
Phibro Animal Health North America, select export markets Veterinary, pet flea control ~15-20%
Elanco Animal Health Global (focus on veterinary products) Veterinary antiparasitics ~10-15%
Koppert Biological Systems Europe, Latin America, Asia Agricultural biological pest control ~5-10%
Certis USA North America, parts of Europe Crop pest management ~5-10%
BASF Global Crop protection ~5-10%

Production and Supply Chain

Most suppliers source S. spinosa strains for fermentation from specialized biotech firms or in-house research, then produce spinosad via fermentation processes. The supply chain faces disruptions due to:

  • Raw material shortages (fermentation media components).
  • Regulatory approvals, affecting product registration and market access.
  • Growing demand in organic farming, which increases competition among suppliers.

Market Trends & Regulatory Environment

  • The global market for spinosad-based products was valued at approximately $200 million in 2021, with a compound annual growth rate of 6-8% projected through 2026 [1].
  • Regulatory approvals vary by country; for example, the U.S. EPA classifies spinosad as a reduced-risk pesticide, easing registration for agricultural use [2].
  • Increasing adoption in organic farming boosts demand, influencing suppliers to expand production capacities.

Key Considerations for Buyers

  • Differentiation by formulation, such as aqueous concentrates or wettable powders.
  • Certificate of analysis, compliance with local regulations.
  • Supply continuity, especially amid global supply chain challenges.
  • Cost competitiveness, influenced by fermentation yields and regulatory costs.

Summary

While multiple suppliers produce spinosad for agricultural and veterinary markets, the leading global producer is Corteva Agriscience (formerly part of Dow AgroSciences). Veterinary-grade spinosad is primarily supplied by Elanco and Phibro. The agricultural sector displays dominance by Corteva, with a growing niche in biopesticide applications served by Koppert and Certis USA.


Key Takeaways

  • Corteva Agriscience is the dominant global producer for spinosad.
  • Veterinary applications are supplied mainly by Elanco and Phibro.
  • Supply chain disruptions can impact availability; demand driven by organic farming supports growth.
  • Regulatory classification in developed markets facilitates market expansion.
  • The market is expected to grow at 6-8% annually through 2026.

FAQs

Q1: Are there synthetic alternatives to spinosad with similar efficacy?
A: Yes. Alternatives include abamectin and spinetoram, which offer comparable pest control but differ in spectrum and safety profiles.

Q2: What are the primary applications of spinosad?
A: It is used in agriculture for pest control, in veterinary medicine for flea treatment, and in some biopesticide formulations.

Q3: How does regulation influence spinosad supply?
A: Regulatory approvals impact market access; in the U.S., the EPA’s classification as a reduced-risk pesticide facilitates wider use and commercialization.

Q4: What are the main regions where spinosad demand is increasing?
A: North America, Europe, and parts of Asia, driven by organic agricultural practices and sustainable pest management policies.

Q5: Can new suppliers enter the market easily?
A: Entry challenges include developing fermentation capacity, obtaining regulatory approvals, and establishing distribution channels.


References

[1] MarketsandMarkets. (2022). Biopesticides Market by Type, Crop Type, and Region – Global Forecast to 2026.

[2] U.S. Environmental Protection Agency. (2022). Spinosad Registration Review.

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