Last updated: April 24, 2026
Who Supplies Phentolamine Mesylate for Pharmaceutical Use?
Phentolamine mesylate is supplied through two main channels: (1) API manufacturers producing phentolamine mesylate (or phentolamine base then converting to the mesylate salt) and (2) specialty chemical houses distributing phentolamine mesylate under commercial catalogs. The supplier footprint is fragmented by geography, regulatory standing, and whether the product is sold as a GMP API, a non-GMP research chemical, or an intermediate.
Which suppliers sell phentolamine mesylate as a catalog chemical?
The following organizations list phentolamine mesylate for sale (typically for research, analytic, or commercial chemical use; GMP status depends on the specific SKU and sales contract):
| Supplier |
Catalog positioning (typical) |
What they sell (as listed) |
Evidence |
| Cayman Chemical |
Research reagent |
Phentolamine mesylate |
Cayman product page lists “Phentolamine mesylate” [1] |
| MedChemExpress (MCE) |
Research reagent |
Phentolamine mesylate |
MCE product page lists “Phentolamine mesylate” [2] |
| TCI Chemicals |
Chemical supplier |
Phentolamine mesylate |
TCI product page lists “Phentolamine mesylate” [3] |
| AbMole Bioscience |
Research reagent |
Phentolamine mesylate |
AbMole product listing includes “Phentolamine mesylate” [4] |
| Bachem (BACHEM AG) |
Specialty chemicals |
Salt forms including mesylates (phentolamine mesylate listed by catalog) |
Bachem product listing shows “Phentolamine mesylate” [5] |
Which suppliers are active in phentolamine mesylate API supply chains?
For API procurement and development, buyers typically require GMP documentation (DMF or CoA at minimum, with CEP/IMPD support where applicable). The most reliable way to identify GMP API suppliers is through: (a) drug master file repositories, (b) WHO/EMA/NMPA listing databases, and (c) direct supplier qualification packs. In the public domain, many API producers do not list “phentolamine mesylate” explicitly on generic marketing pages, and GMP claims are often SKU-dependent.
In this dataset, the suppliers with clearly attributable public product listings include reagent/specialty chemical channels listed above, but the sources cited do not provide explicit GMP status per SKU for all parties.
What specs do buyers typically require from phentolamine mesylate suppliers?
Even when marketed as a catalog chemical, buyers for clinical or commercial formulation generally specify:
- Identity: IR and/or NMR, LC-MS for confirmation of salt form
- Purity/impurities: assay threshold and impurity profile by HPLC (common buyer targets often fall in the “pharma grade” range; exact numbers are supplier-SKU specific)
- Solvent and residuals: residual solvents per ICH Q3C, water content (Karl Fischer or equivalent)
- Salt form confirmation: verification that the marketed product is mesylate salt (not free base)
- Particle and physical properties (when relevant): particle size distribution for formulation handling
- Regulatory package: CoA, traceability, and for GMP use, GMP manufacturing evidence and regulatory dossier access
The critical commercial question is not whether a supplier sells “phentolamine mesylate,” but whether it supplies GMP API with the documentation and impurity profile required by the intended drug product program.
How to map suppliers to procurement use-cases
| Procurement use-case |
Best-fit supplier channel |
Required diligence |
| Analytical reference standards |
Research reagent suppliers |
CoA, IR/NMR match, batch-to-batch consistency |
| Nonclinical formulation work |
Catalog chemical suppliers |
Basic impurity control and specification alignment |
| Clinical/commercial API |
GMP API supply chain |
GMP status, DMF/CEP, audit report, full impurity panel |
Supplier short list for immediate sourcing (publicly listed)
These suppliers have publicly visible product listings for phentolamine mesylate:
- Cayman Chemical [1]
- MedChemExpress (MCE) [2]
- TCI Chemicals [3]
- AbMole Bioscience [4]
- Bachem [5]
Key Takeaways
- Publicly listed suppliers for phentolamine mesylate include Cayman Chemical, MedChemExpress, TCI Chemicals, AbMole Bioscience, and Bachem.
- Public listings show availability, not necessarily GMP API status. GMP readiness depends on the specific SKU and the regulatory documentation supplied under contract.
- For development programs, procurement should separate reference/reagent sourcing from GMP API qualification, then align specifications to identity, salt form, impurity profile, residual solvents, and required regulatory documentation.
FAQs
1) Are Cayman Chemical, TCI, and MCE sellers of GMP phentolamine mesylate API?
Their public pages confirm product availability, but GMP API status is not established in the cited sources and depends on the specific offering and documentation provided in the sales contract [1] [2] [3].
2) Do these suppliers sell phentolamine mesylate specifically as the mesylate salt?
Their catalog listings are for the salt form “phentolamine mesylate” by name on product pages [1] [2] [3] [4] [5].
3) Which supplier is best for procurement of phentolamine mesylate as a chemical reference?
Research reagent suppliers such as Cayman Chemical and MCE are positioned for reagent/reference use based on their catalog structure [1] [2].
4) Can I source phentolamine mesylate for formulation work from any catalog chemical supplier?
Formulation use requires specification alignment on purity, impurities, and residuals. The cited sources confirm listings but do not provide full formulation-grade specifications [1] [3].
5) How many suppliers are publicly listed in the cited sources?
Five: Cayman Chemical, MedChemExpress, TCI Chemicals, AbMole Bioscience, and Bachem [1] [2] [3] [4] [5].
References (APA)
[1] Cayman Chemical. (n.d.). Phentolamine mesylate. Cayman Chemical. https://www.caymanchem.com/
[2] MedChemExpress. (n.d.). Phentolamine mesylate. MedChemExpress. https://www.medchemexpress.com/
[3] TCI Chemicals. (n.d.). Phentolamine mesylate. TCI. https://www.tcichemicals.com/
[4] AbMole Bioscience. (n.d.). Phentolamine mesylate. AbMole Bioscience. https://www.abmole.com/
[5] Bachem. (n.d.). Phentolamine mesylate. Bachem. https://www.bachem.com/
