Last updated: April 25, 2026
What supplier categories handle mec amylamine hydrochloride?
Mecamylamine hydrochloride (CAS 134-10-3; formula C8H17Cl2N) is supplied through three common commercial pathways:
- Specialty fine-chemical distributors (catalog purchase, small-to-mid scale)
- API and chemical manufacturers (bulk API-grade or custom synthesis)
- Intermediates and custom synthesis providers (route development, analog manufacturing, packaging to spec)
Which suppliers bring mec amylamine hydrochloride to market via catalog distribution?
Catalog distribution typically lists the compound as “Mecamylamine hydrochloride” or “Mecamylamine HCl”. Common distributor channels include:
- MedChemExpress
- Cayman Chemical
- TCI Chemicals
- Sigma-Aldrich (Merck)
- Apollo Scientific
- Chem-Impex
- Selleck Chemicals
Because distributor inventories change by region, these sources function best as a starting point for availability checks and documentation package requests (CoA, analytical method, and traceability).
Which manufacturers supply mec amylamine hydrochloride at bulk/API scale?
Bulk supply is typically handled by API or fine-chemical manufacturers that can provide:
- CoA with assay and impurity profile
- GMP where applicable
- DMF/CEP support where applicable
- Stability and packaging validation support when applicable
The most reliable supplier set for bulk is obtained from:
- API procurement networks
- GMP multi-product chemical manufacturers
- Custom synthesis providers with documented batch history for this scaffold
How to assess supplier quality for mec amylamine hydrochloride (purchase-ready criteria)
Procurement decisions for mec amylamine hydrochloride usually hinge on these documents and specs:
| Evaluation point |
What to demand |
Why it matters |
| Identity |
IR/1H NMR and analytical confirmation |
Prevents isomer or salt-form mismatch |
| Purity/assay |
CoA assay value (percent) |
Controls dose uniformity and downstream yield |
| Impurities |
Total impurities and specified thresholds |
Drives qualification for formulation |
| Salt form |
Confirmation it is hydrochloride |
Avoids potency variance from freebase vs salt |
| Particle/handling |
Physical form (crystalline powder), moisture guidance |
Impacts dissolution and stability |
| Regulatory package |
GMP/DMF/CoA traceability |
Determines whether it fits clinical/commercial needs |
| Shipping |
Incoterms and temperature/moisture packaging |
Reduces degradation and rework |
Supplier shortlist logic: what to target first
For most projects involving mec amylamine hydrochloride, the highest-throughput supplier path is:
- Start with major catalog distributors for fast lead time and documentation.
- Move to bulk/API-capable manufacturers if the intended use requires higher lot-to-lot consistency, controlled impurities, and supply continuity.
Key Takeaways
- Mecamylamine hydrochloride is typically sourced from catalog distributors and bulk/API or custom synthesis manufacturers.
- The procurement-ready path is driven by CoA quality, impurity profile, salt confirmation, and documentation support.
- For earliest availability, target established fine-chemical distributors; for scale and compliance, qualify bulk/API-capable manufacturers.
FAQs
1) What is the standard chemical name used by suppliers?
“Mecamylamine hydrochloride” or “Mecamylamine HCl” are the common catalog names.
2) What CAS number identifies the correct compound?
134-10-3.
3) Do suppliers provide GMP-level mec amylamine hydrochloride by default?
Some suppliers do, but GMP availability depends on the specific manufacturing site and lot. The procurement requirement should be aligned to the intended regulatory stage.
4) Why does salt-form verification matter?
Mecamylamine can exist as different salt forms or as freebase; potency and formulation behavior change with the correct salt identity.
5) What documents should be requested before placing a larger order?
CoA with assay and impurities, identity confirmation (often IR and NMR), and salt-form specification.
References
[1] MedChemExpress. Mecamylamine hydrochloride product listing (catalog name and details).
[2] Cayman Chemical. Mecamylamine hydrochloride product listing (catalog details).
[3] TCI Chemicals. Mecamylamine hydrochloride product listing (catalog details).
[4] Merck/Sigma-Aldrich. Mecamylamine hydrochloride product listing (catalog details).
[5] Apollo Scientific. Mecamylamine hydrochloride product listing (catalog details).
[6] Chem-Impex. Mecamylamine hydrochloride product listing (catalog details).
[7] Selleck Chemicals. Mecamylamine hydrochloride product listing (catalog details).
