Last updated: April 27, 2026
What companies supply ISOVUE-370 (iopamidol injection)?
ISOVUE-370 is an iodinated contrast agent product. In the US market, it is distributed and supplied by Bristol Myers Squibb (BMS) under the ISOVUE brand for iopamidol injection.
What does the supply chain look like for ISOVUE-370?
For an injectable small molecule like iopamidol, the practical “supplier” set for procurement usually breaks into three layers:
- Marketing authorization holder / product label holder (brand owner and finished drug supplier)
- Contract manufacturing and packaging (finished dosage form)
- API and key intermediate suppliers (iopamidol manufacturing inputs)
1) Finished dose supplier (label holder / marketer)
| Supply layer |
Entity |
Role |
Evidence |
| Finished drug supply (US) |
Bristol Myers Squibb |
ISOVUE-370 label holder and market supplier |
ISOVUE brand labeling and FDA-registered drug listing under BMS |
Which suppliers provide iopamidol API and intermediates?
No complete, definitive supplier roster for iopamidol API and intermediates tied specifically to ISOVUE-370 is available from the public-facing record set typically used in public patent landscaping. Public FDA documents and patent records generally disclose the product and manufacturing site(s) without producing a consolidated list of all upstream chemical suppliers for intermediates used to make iopamidol.
What can be identified reliably from public records?
Public records can usually support:
- Who markets ISOVUE-370
- Whether the product is made and packaged at registered manufacturing sites
- The presence of contract manufacturing relationships at the site level
However, upstream chemical suppliers for iopamidol intermediates are not consistently published in a supplier list that maps cleanly to ISOVUE-370 batches.
How to treat “suppliers” for ISOVUE-370 in procurement terms
For commercial sourcing, buyers typically treat the following as “suppliers”:
A) Finished-dose supplier (direct procurement)
- Bristol Myers Squibb (US brand supplier for ISOVUE-370)
B) Manufacturing site suppliers (contract manufacturing)
- Identified via FDA drug establishment registrations for the product strength and dosage form
- Use this to qualify GMP manufacturing capacity, not to identify chemical raw material vendors
C) API and intermediate suppliers
- Qualified via supplier qualification packages and CoAs, or by reviewing DMF/ASMF-related documentation under appropriate regulatory channels
- Not generally exposed as a public “who supplies iopamidol to ISOVUE-370” list
Key Takeaways
- Bristol Myers Squibb is the finished-product supplier/label holder for ISOVUE-370 in the US market.
- Public sources support product-level supplier identification (brand holder) and can support site-level manufacturing identification through FDA establishment records.
- Public sources do not provide a consistent, complete, batch-to-product upstream list of API and intermediate chemical suppliers specifically tied to ISOVUE-370.
FAQs
Who supplies ISOVUE-370 in the US?
Bristol Myers Squibb supplies ISOVUE-370 as the label holder and market marketer.
Is iopamidol the active ingredient in ISOVUE-370?
Yes. ISOVUE-370 is an injection of iopamidol at 370 mg iodine/mL.
Can upstream iopamidol API suppliers be identified from public sources?
Not in a complete, product-mapped supplier list. Public records more reliably support brand holder and registered manufacturing sites than upstream chemical vendor rosters.
How do you identify who manufactures ISOVUE-370?
Use FDA drug establishment registration records and product listings to identify registered manufacturing and packaging sites associated with the product.
What is the best procurement definition of “supplier” for ISOVUE-370?
Treat the supplier as the finished-dose label holder/marketer for purchasing, and use GMP manufacturing site registration for manufacturing qualification; upstream chemical sourcing requires supplier qualification and regulatory documentation.
References
[1] U.S. Food and Drug Administration. Drug databases and label information for ISOVUE-370 (iopamidol injection). FDA Drug Registration and Listing / product labeling records.
