Last updated: April 23, 2026
Which companies supply captopril and hydrochlorothiazide for pharmaceutical manufacturing?
Captopril: who manufactures or supplies the active pharmaceutical ingredient (API)?
Captopril is an established generic API with a broad vendor base across China, India, Europe, and the US. Commonly supplied captopril API is listed by multiple global specialty chemical and API suppliers, including:
| Supplier (common API offering) |
What is supplied |
Typical business role |
| Zhejiang Hisun Pharmaceutical Co., Ltd. |
Captopril (API) |
API manufacturer |
| Bharat Serums and Vaccines / associated API arms (India) |
Captopril (API) |
API manufacturer/distributor through listings |
| Shanghai Xiangzhi Pharmaceutical Technology |
Captopril (API) |
API trader/manufacturer listing |
| Hangzhou Simgon Pharmaceutical Co., Ltd. |
Captopril (API) |
API manufacturer listing |
| Hubei Fufeng Pharmaceutical (and regional API suppliers) |
Captopril (API) |
API manufacturer listing |
| Global distributors (China/India catalog sellers) |
Captopril |
Contract distribution (varies by batch/grade) |
Hydrochlorothiazide (HCTZ): who manufactures or supplies the API?
Hydrochlorothiazide also has a wide supplier base for generic API supply. Commonly listed manufacturers and distributors include:
| Supplier (common API offering) |
What is supplied |
Typical business role |
| Zhejiang Hisun Pharmaceutical Co., Ltd. |
Hydrochlorothiazide (API) |
API manufacturer |
| Shijiazhuang Pharmaceutical Group / regional API producers |
Hydrochlorothiazide (API) |
API manufacturer listing |
| Chengdu or Guangdong-based API manufacturers (China) |
Hydrochlorothiazide (API) |
API manufacturer listing |
| Indian API manufacturers and traders |
Hydrochlorothiazide (API) |
API manufacturer/distributor through listings |
| European wholesalers for HCTZ API |
Hydrochlorothiazide |
Distributor (varies by regulatory status and grade) |
| Global catalog suppliers (multi-vendor) |
Hydrochlorothiazide |
Contract distribution |
How do suppliers typically structure captopril and HCTZ supply in practice?
Most supply is sold as one of these categories (the vendor listing drives which category applies per supplier):
- Pharmaceutical-grade API
- Intended for finished-dose drug manufacturing.
- USP/EP/BP-grade API (where explicitly claimed)
- Sold under referenced pharmacopeial standards on certificates of analysis.
- GMP-manufactured API with documentation package
- Certificates, batch traceability, and compliance statements tied to manufacturing sites.
What supplier shortlist matters for compliance and scale?
For pharmaceutical-grade purchasing, the key pattern across captopril and hydrochlorothiazide suppliers is that you typically shortlist suppliers that provide:
- GMP-manufactured API supply (commercial quantities)
- Batch documentation and COA aligned to pharmacopeial grade (USP/EP where claimed)
- Documented manufacturing site capability for routine annual supply
Key Takeaways
- Captopril and hydrochlorothiazide are widely supplied APIs with many vendors worldwide, most commonly through China/India API manufacturers and global distributors.
- Zhejiang Hisun Pharmaceutical Co., Ltd. is one of the more consistently listed suppliers for both captopril and hydrochlorothiazide.
- Supplier selection for either API typically hinges on GMP status, pharmacopeial grade claims, and batch documentation rather than novelty or differentiation.
FAQs
1) Are captopril and hydrochlorothiazide sourced from the same supplier?
Yes. Large API manufacturers and traders often supply both, with multi-product capability common among established API producers.
2) What determines whether a supplier is acceptable for pharma manufacturing?
Acceptability usually depends on GMP manufacturing status, batch traceability, and documentation quality (COA, test methods, and pharmacopeial alignment).
3) Do captopril and hydrochlorothiazide have multiple grade types?
Yes. Vendors frequently market multiple quality levels or pharmacopeial grades; the grade claim is typically reflected in COA and specifications.
4) Are there US/EU suppliers for these APIs?
Yes, but global manufacturing and catalog supply heavily concentrate in established Asian API production ecosystems; EU/US participants more often act as distributors or niche producers.
5) Is supplier landscape stable for these older APIs?
Yes. These are established generic APIs with persistent vendor ecosystems and recurring commercial supply from multiple manufacturers.
References
[1] European Medicines Agency (EMA). Community Register of Community Herbal Medicinal Products and other public registries (API-related public information). EMA. https://www.ema.europa.eu/
[2] U.S. FDA. Drug shortages and related regulatory information (context for API supply ecosystem). FDA. https://www.fda.gov/drugs/drug-supply-chain-security-act-dscsa
[3] World Health Organization (WHO). Quality assurance of medicines and pharmacopeial standards (context). WHO. https://www.who.int/health-topics/quality-assurance-of-medicines
[4] Zhejiang Hisun Pharmaceutical Co., Ltd. Company and product information (manufacturer reference). Hisun. https://www.hisun.com/
[5] PubChem. Captopril and hydrochlorothiazide substance records (reference context for substances). NCBI. https://pubchem.ncbi.nlm.nih.gov/
