Last updated: April 25, 2026
Who supplies Avalide to markets?
Avalide is marketed as a fixed-dose combination of irbesartan and hydrochlorothiazide. In practice, the “supplier” chain splits into two layers: (1) the legal marketing authorization holder (MAH) / brand owner in each country and (2) contract manufacturing and packaging networks that can vary by geography.
The information required to name specific, country-specific suppliers (MAH, contract manufacturers, and drug substance suppliers) is not present in the input provided. Without that, it is not possible to produce a complete and accurate supplier list.
Who supplies irbesartan (drug substance)?
Avalide’s active ingredient irbesartan is sourced from branded and generic irbesartan API manufacturers. A supplier-grade answer requires:
- the API manufacturer(s) tied to the relevant product dossier(s), and
- the particular grade/specification used (salt form, impurity profile, and particle spec).
Those dossier-level facts are not included in the request.
Who supplies hydrochlorothiazide (drug substance)?
Hydrochlorothiazide is widely supplied globally, but supplier identification still requires dossier or packaging-level traceability for the specific Avalide product line (by country, strength, and manufacturer). No such product-line detail is included in the request.
Who supplies finished-dose manufacturing and packaging?
Finished-dose supplier identity depends on the exact:
- country market,
- strength (Avalide typically includes multiple strengths),
- marketing authorization, and
- manufacturing site (often changes across launch cycles and line upgrades).
No geography, strength, or MAH/manufacturing site data is included, so a definitive supplier list cannot be produced from the provided information.
Key Takeaways
- “Suppliers for Avalide” must be defined as MAH/brand owner, finished-dose manufacturer, and API suppliers.
- The input contains no country, no strength, no MAH, and no dossier/manufacturing-site identifiers, so a complete and accurate supplier mapping cannot be generated.
- A correct supplier answer requires dossier-linked traceability for irbesartan API, hydrochlorothiazide API, and the finished-dose manufacturing and packaging sites.
FAQs
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What does Avalide consist of?
Avalide is a fixed-dose combination of irbesartan and hydrochlorothiazide.
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Is there one global supplier for Avalide?
No. Avalide supply typically varies by country market and manufacturing authorization.
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Do irbesartan and hydrochlorothiazide come from the same suppliers?
Not necessarily. API supply chains for each component can be independent.
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Does the finished-dose supplier stay the same over time?
It can change due to contract manufacturing shifts, line upgrades, and regulatory manufacturing transfers.
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How are supplier identities verified for high-stakes decisions?
Through regulatory dossier traceability (MAH and manufacturing sites) and API supplier linkage to the specific product registration.
References
[1] FDA Orange Book. (n.d.). Drug Products Listed in the Orange Book. U.S. Food and Drug Administration. https://www.accessdata.fda.gov/scripts/cder/ob/
[2] EMA. (n.d.). European Medicines Agency: Medicines. European Medicines Agency. https://www.ema.europa.eu/en/medicines
[3] DailyMed. (n.d.). Labeling for Avalide (irbesartan and hydrochlorothiazide). U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/
