Last updated: May 25, 2026
Executive summary: Public supplier identification for “Advil Allergy and Congestion Relief” is limited by product-level branding that typically maps to specific active ingredients and dosage forms (most commonly an NSAID plus an antihistamine and/or decongestant, depending on country). Without the exact formulation strength (active ingredient list) and dosage form (capsules, tablets, liquids, gels), supplier attribution at the manufacturer, contract-manufacturer, and packaging levels cannot be stated accurately.
Who supplies Advil Allergy and Congestion Relief in the US?
Short answer: “Advil Allergy and Congestion Relief” is marketed under the Advil brand by distributors that may not manufacture the product themselves. The actual drug substance and finished-dose manufacturing suppliers depend on the specific NDC and formulation.
What “supplier” usually means for this branded product
- Labeler/distributor (FDA drug product label “Holder”): the company responsible for the marketed product in the US.
- Finished dosage manufacturer (FD&C Act label section “Manufactured for” / “Manufactured by”): the contract manufacturer or in-house site making the finished dosage form.
- Packaging supplier (secondary packaging): often not disclosed in public data except via label statements or commercial packaging records.
- Drug substance supplier: often not publicly listed for consumer OTC products unless explicitly shown on packaging or in regulatory filings.
Why formulation and NDC matter
Even under the same brand family, OTC combo products can vary by:
- active ingredients used (e.g., ibuprofen only vs ibuprofen plus antihistamine and decongestant)
- tablet vs caplet vs liquid
- strength (mg per dose)
- country and market authorization
Which companies are listed on the Advil Allergy and Congestion Relief label as manufacturers?
Short answer: Manufacturer and “distributed by” lines are label-specific. Supplier identification requires the exact product label text tied to a specific NDC/strength.
Label text categories used by OTC products
- “Manufactured for: [company]”
- “Manufactured by: [company]”
- “Distributed by: [company]”
- “Packaged by: [company]”
Typical supplier patterns for Advil-branded OTC
- Primary brand owner acts as labeler/distributor.
- Finished-dose manufacturing is commonly outsourced to contract manufacturing networks or performed in owned plants, with supplier names appearing in “manufactured for” language on the carton/package insert.
What are the active ingredients and how do they change the supplier network?
Short answer: Supplier networks differ because different active ingredients require different drug substance suppliers and finished-dose formulation expertise.
Key supplier-impact variables
- NSAID component (ibuprofen): requires GMP drug substance sourcing and standard OTC solid-dose manufacturing.
- Antihistamine component: introduces compatibility and stability constraints.
- Decongestant component: adds additional granulation, dissolution, and moisture-sensitivity considerations.
- Combination excipient set: changes blending time, tablet press parameters, coating suppliers, and packaging material selection.
What NDC-level suppliers exist for Advil Allergy and Congestion Relief?
Short answer: NDC-level supplier lists are not derivable from brand name alone.
How NDC ties to supplier identification
For OTC drug products, the FDA’s structured product labeling and NDC listings normally tie:
- labeler name
- manufacturer/packer (where disclosed)
- dosage form and strength
Supplier mapping approach used in competitive intelligence
- Identify the exact NDC by strength and dosage form.
- Pull the labeler and manufacturer/packer fields tied to that NDC.
- Extract “manufactured for” entities from the carton/label text.
How do contract manufacturing and packaging suppliers work for OTC combination products?
Short answer: OTC combo products often use contract manufacturing for scale and product-line flexibility, plus packaging partners for blistering, bottle filling, and secondary packaging.
Common outsourcing segments
- Tablet/caplet production (blending, compression, coating)
- Encapsulation (if caplets/capsules)
- Liquid fills (if a suspension or syrup)
- Bottling, blistering, unit-dose packaging
- Tamper-evident and child-resistant packaging compliance
Supplier bottlenecks
- blister foil and lidding film supply
- desiccant selection for moisture-sensitive decongestant combinations
- QA release capacity during seasonal demand spikes
What suppliers can enter as generics for the same Advil Allergy and Congestion Relief composition?
Short answer: If the product’s active ingredient combination is not protected by strong formulation or method patents (and regulatory exclusivities are not blocking), multiple API and finished-dose manufacturers can supply equivalents once permitted. But supplier eligibility is tied to:
- the approved OTC monograph or NDA type product pathway (depending on jurisdiction)
- bioequivalence requirements (if applicable)
- labeling compliance for OTC drug facts
Practical implication
Competitive supply typically comes from:
- alternative tablet makers for the same dosage form
- alternative blister/bottle packaging lines
- API suppliers that meet pharmacopeia and regulatory standards
What is the Orange Book status for Advil Allergy and Congestion Relief suppliers?
Short answer: OTC combination products are frequently not listed in the FDA Orange Book in the way prescription NDA/BLA drugs are. If the product is an OTC monograph drug, Orange Book listings may not exist.
Why Orange Book status may be irrelevant for OTC brands
- Many OTC drugs rely on OTC monograph status instead of NDA/BLA approvals.
- Orange Book typically covers approved drug products with application-based exclusivity and patent listings.
Key takeaways
- “Advil Allergy and Congestion Relief” is a brand name that does not uniquely identify the active ingredient set, strength, or NDC.
- Supplier identification (manufacturer, packer, labeler) is label/NDC-specific and cannot be reliably attributed from the brand name alone.
- Supplier networks for OTC combo products vary by API set, formulation type, and packaging format.
FAQs
1) How do I find the manufacturer of Advil Allergy and Congestion Relief if I only have the box?
Use the strength and dosage form on the carton to identify the NDC, then read the “Manufactured for” or “Manufactured by” line.
2) Are the suppliers different across tablets vs liquids under the same Advil Allergy and Congestion Relief brand?
Yes. Different dosage forms usually imply different finished-dose manufacturing lines and packaging partners.
3) Does Advil Allergy and Congestion Relief have Orange Book patents that control generic supply?
Often not in the Orange Book format for OTC monograph products. Patent or exclusivity control depends on the exact regulatory status of the product.
4) Who supplies the ibuprofen used in Advil Allergy and Congestion Relief?
Drug substance suppliers are commonly not identified publicly; they are typically covered only if explicitly stated on packaging or in certain regulatory/contract disclosures.
5) What drives supplier risk for seasonal OTC allergy and congestion products?
Packaging-material capacity, API lead times for the decongestant/antihistamine components, and finished-dose QA release capacity during peak demand.
References
- U.S. FDA. Orange Book: Approved Drug Products with Therapeutic Equivalence Evaluations. (FDA database).
- U.S. FDA. National Drug Code (NDC) Directory. (FDA database).
