Last updated: February 20, 2026
Acetylcholine chloride is a synthetic neurotransmitter used primarily in research, pharmacology, and electrophysiology. The following list highlights key global suppliers providing pharmaceutical-grade or research-grade acetylcholine chloride.
Major Suppliers of Acetylcholine Chloride
1. Sigma-Aldrich (Merck KGaA)
- Product Name: Acetylcholine chloride, for research
- Purity: Typically ≥98%
- Package Sizes: Ranges from 10 mg to 25 g
- Certifications: CE, ISO compliant
- Regional Availability: Worldwide
2. Tocris Bioscience (A part of Bio-Techne)
- Product Name: Acetylcholine chloride
- Purity: ≥98%
- Package Sizes: 10 mg, 50 mg, 100 mg
- Applications: Research, electrophysiology
- Regional Coverage: North America, Europe, Asia
3. Thermo Fisher Scientific
- Product Names: Acetylcholine chloride, for electrophysiology
- Purity: ≥98%
- Packaging: 10 mg, 50 mg, 100 mg
- Use: Neuroscience research, pharmacology
4. MP Biomedicals
- Product Name: Acetylcholine chloride
- Purity: ≥98%
- Package Sizes: 50 mg, 250 mg
- Application: In vitro studies
5. Cayman Chemical
- Product Name: Acetylcholine chloride
- Purity: ≥98%
- Package Sizes: 10 mg, 50 mg
- Usage: Pharmacological research
Specialty and Custom Suppliers
6. APExBIO
- Offering: Research-grade acetylcholine chloride
- Purity: ≥98%
- Package Sizes: 10 mg to 100 mg
- Region: US, online ordering
7. Sigma-Aldrich (Custom synthesis and formulations)
- Provides custom purity levels and tailored formulations for specific research needs.
Criteria for Supplier Selection
- Certifications: ISO 9001, cGMP compliance for pharmaceutical-grade products.
- Purity Levels: Typically ≥98%, with higher grades available.
- Regulatory Approvals: CE marking, FDA compliance for certain suppliers.
- Delivery Turnaround: Generally ranges from 2 to 4 weeks depending on region and order size.
- Pricing: Competitive; varies based on purity, quantity, and contractual agreements.
Market Considerations
- Dip in supply chains for research chemicals can impact availability.
- Increasing demand from neuroscience research drives continuous procurement.
- Synthesis quality and certification influence selection for clinical versus research applications.
Summary
Major global distributors such as Sigma-Aldrich, Tocris, Thermo Fisher Scientific, MP Biomedicals, and Cayman Chemical supply acetylcholine chloride with high purity levels primarily for research use. Regional suppliers like APExBIO expand access through online channels. Regulated pharmaceutical-grade equivalents are offered by fewer suppliers, often requiring adherence to strict quality standards.
Key Takeaways
- Acetylcholine chloride is widely available through major research suppliers.
- Focus on purity (≥98%) for research, higher standards for clinical applications.
- Regional distribution influences delivery speed and price.
- Certification and regulatory status are critical for pharmaceutical-grade supply.
- Demand in neuroscience research sustains supply chain stability.
FAQs
Q1: Is acetylcholine chloride suitable for human therapeutic use?
Not directly. It is primarily used in research and laboratory settings. For therapeutic applications, specific formulations and regulatory approvals are required.
Q2: What purity levels are necessary for electrophysiology experiments?
Typically, ≥98% purity is sufficient, but some experiments may require ≥99% purity for higher accuracy.
Q3: Are there synthetic alternatives to acetylcholine chloride?
Yes. Acetylcholine analogs such as carbachol exist, which are more stable and used in similar research contexts.
Q4: What are the storage conditions for acetylcholine chloride?
Store in a tightly sealed container, protected from light, at 2-8°C. Stable for several years under proper storage.
Q5: Can I order acetylcholine chloride online from suppliers?
Yes. Suppliers like Sigma-Aldrich, Tocris, and APExBIO offer online purchasing for research purposes, with delivery worldwide.
References
- Sigma-Aldrich. (2023). Acetylcholine chloride product information. Retrieved from https://www.sigmaaldrich.com
- Tocris Bioscience. (2023). Acetylcholine chloride product sheet. Retrieved from https://www.tocris.com
- Thermo Fisher Scientific. (2023). Neurotransmitter reagents catalog. Retrieved from https://www.thermofisher.com
- MP Biomedicals. (2023). Acetylcholine chloride datasheet. Retrieved from https://www.mpbio.com
- Cayman Chemical. (2023). Acetylcholine chloride product information. Retrieved from https://www.caymanchem.com
