Last Updated: November 10, 2026

Details for Patent: RE44186

Name: Drug Patent Intelligence for US Patent RE44186
Creator: DrugPatentWatch
License: https://www.drugpatentwatch.com/terms.php

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Summary for Patent: RE44186

Title:	Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
Abstract:	Dipeptidyl peptidase IV (DP 4) inhibiting compounds are provided having the formula where A method is also provided for treating diabetes and related diseases, especially Type II diabetes, and other diseases as set out herein, employing such DP 4 inhibitor *or a combination of such DP 4 inhibitor and one or more of another antidiabetic agent such as metformin, glyburide, troglitazone, pioglitazone, rosiglitazone and/or insulin and/or one or more of a hypolipidemic agent and/or anti-obesity agent and/or other therapeutic agent.
Inventor(s):	Jeffrey A. Robl, Richard B. Sulsky, David J. Augeri, David R. Magnin, Lawrence G. Hamann, David A. Betebenner
Assignee:	AstraZeneca AB
Application Number:	US13/308,658
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent RE44186
Patent Claim Types: see list of patent claims	Use; Composition;

Drugs Protected by US Patent RE44186

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent RE44186

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
European Patent Office	1261586	⤷ Start Trial	C300436	Netherlands	⤷ Start Trial
European Patent Office	1261586	⤷ Start Trial	CA 2010 00007	Denmark	⤷ Start Trial
European Patent Office	1261586	⤷ Start Trial	91650	Luxembourg	⤷ Start Trial
European Patent Office	1261586	⤷ Start Trial	SPC005/2010	Ireland	⤷ Start Trial
European Patent Office	1261586	⤷ Start Trial	10C0010	France	⤷ Start Trial
European Patent Office	1261586	⤷ Start Trial	SPC/GB10/001	United Kingdom	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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