Last Updated: September 27, 2026

Details for Patent: 9,744,181

Name: Drug Patent Intelligence for US Patent 9744181
Creator: DrugPatentWatch
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Summary for Patent: 9,744,181

Title:	Compositions and methods for combination antiviral therapy
Abstract:	The present invention relates to therapeutic combinations of [2-(6-amino-purin-9 yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropoxycarbonyloxymethyl ester (tenofovir disoproxil fumarate, Viread®) and (2R,5S,cis)-4-amino-5-fluoro-1-(2 hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one (emtricitabine, Emtriva™, (−)-cis FTC) and their physiologically functional derivatives. The combinations may be useful in the treatment of HIV infections, including infections with HIV mutants bearing resistance to nucleoside and/or non-nucleoside inhibitors. The present invention is also concerned with pharmaceutical compositions and formulations of said combinations of tenofovir disoproxil fumarate and emtricitabine, and their physiologically functional derivatives, as well as therapeutic methods of use of those compositions and formulations.
Inventor(s):	Terrence C. Dahl, Mark M. Menning, Reza Oliyai
Assignee:	Gilead Sciences Inc
Application Number:	US14/523,783
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 9,744,181
Patent Claim Types: see list of patent claims	Use; Dosage form;

Drugs Protected by US Patent 9,744,181

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 9,744,181

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
African Regional IP Organization (ARIPO)	2089	⤷ Start Trial
Argentina	040805	⤷ Start Trial
Argentina	043332	⤷ Start Trial
Argentina	101679	⤷ Start Trial
Austria	398455	⤷ Start Trial
Australia	2004206821	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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