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Last Updated: April 29, 2024

Details for Patent: 9,708,610

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Summary for Patent: 9,708,610

Title:	Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
Abstract:	The present invention provides compositions comprising at least one oligomeric compound comprising an alternating motif and further include a region that is complementary to a nucleic acid target. The compositions are useful for targeting selected nucleic acid molecules and modulating the expression of one or more genes. In preferred embodiments the compositions of the present invention hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA. The present invention also provides methods for modulating gene expression.
Inventor(s):	Allerson; Charles (San Diego, CA), Bhat; Balkrishen (Carlsbad, CA), Eldrup; Ann B. (Newtown, CT), Manoharan; Muthiah (Weston, MA), Griffey; Richard H. (Visa, CA), Baker; Brenda F. (Carlsbad, CA), Swayze; Eric E. (Encinitas, CA)
Assignee:	Ionis Pharmaceuticals, Inc. (Carlsbad, CA)
Application Number:	14/834,224
Patent Claim Types: see list of patent claims	Use; Composition; Formulation;

Drugs Protected by US Patent 9,708,610

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 9,708,610

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Austria	292141	⤷ Try a Trial
Australia	2003213120	⤷ Try a Trial
Australia	2003248708	⤷ Try a Trial
Australia	2003251524	⤷ Try a Trial
Australia	2003287464	⤷ Try a Trial
Australia	2003287501	⤷ Try a Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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