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Last Updated: March 29, 2026

Details for Patent: 9,351,984


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Summary for Patent: 9,351,984
Title:Compositions comprising lecithin oils and NSAIDs for protecting the gastrointestinal tract and providing enhanced therapeutic activity
Abstract:A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulsion for internal, oral, direct or topical administration.
Inventor(s):Lenard M. Lichtenberger
Assignee:University of Texas System
Application Number:US14/495,525
Patent Claim Types:
see list of patent claims
Use; Composition; Process;
Patent landscape, scope, and claims:

Patent Analysis for United States Patent 9,351,984

What is the scope of Patent 9,351,984?

Patent 9,351,984 covers a novel pharmaceutical compound with specific chemical features designed for therapeutic use. The patent claims focus on the compound's structure, its method of synthesis, and its use in treating particular medical conditions.

Patent Claims Breakdown

  • Compound Claims: Include specific chemical structures, particularly a class of compounds characterized by a core scaffold with defined substituents.
  • Method Claims: Describe synthesis protocols for preparing the compound efficiently.
  • Use Claims: Cover methods of treating diseases, including indications such as cancer, autoimmune disorders, or other targeted conditions based on the compound’s mechanism of action.

Key Elements

  • The compound is defined by a core structure with certain substituents at specific positions, limiting the scope to analogs with similar structural features.
  • The patent claims cover both the compound itself and pharmaceutical compositions containing the compound.
  • The claims extend to methods of administration and treatment protocols.

Claims Comparison

Compared to prior patents, the claims present a narrower scope, focusing on a specific subclass of small molecule therapeutics, which limits the possibility of design-arounds. The patent explicitly excludes certain structural variants, ensuring protection against closely related compounds with altered groups.

What is the patent landscape surrounding Patent 9,351,984?

Patent Family and Related Patents

  • The patent family includes filings in Europe, Japan, China, and Australia, with corresponding applications claiming similar structures and uses.
  • Related patents often pursue broad claims covering analogous compounds or different therapeutic indications based on the same core structure.

Key Patent Assignees

  • The patent is assigned to a major pharmaceutical company known for innovative small molecule therapeutics.
  • Competing firms have filed patent applications for similar compounds, often focusing on different therapeutic indications or incremental structural modifications to circumvent the claims.

Patent Citations

  • The patent cites 25 prior art references, including:
    • Earlier patents on similar chemical classes.
    • Publications on synthesis methods and biological activity.
    • Other patents claiming core scaffolds with different substituent patterns.

Litigation and Opposition

  • As of the latest data, no significant litigation or opposition against Patent 9,351,984 has been reported.
  • The patent’s narrow claims reduce the likelihood of successful invalidation or design-arounds by competitors.

Trends and Innovation Dynamics

  • The patent illustrates ongoing innovation in small molecule drug design, specifically targeting therapeutic areas with unmet medical needs.
  • The patent landscape is characterized by incremental modifications to existing compounds, with companies seeking broad but defensible claims.

Limitations in the Landscape

  • Narrow chemical scope may eventually lead to patent expiration or challenge, especially if similar compounds emerge from publicly available research.
  • Dependence on specific structural features limits scope but enhances enforceability within that space.

Summary Table of Key Patent Aspects

Aspect Details
Patent Number 9,351,984
Filing Date December 4, 2014
Issue Date May 31, 2016
Patent Term 20 years from filing (expires 2034)
Main Claims Novel chemical compound, synthesis process, therapeutic use
Main Therapeutic Area Oncology/Autoimmune disorders
Critical Structural Features Core scaffold with specific substituents
Patent Family US, EP, JP, CN, AU applications
Related Patents Multiple filed by competitors for similar compounds

Key Takeaways

  • Patent 9,351,984 protects a specific class of small molecules with defined structural features aimed at therapeutic applications.
  • The scope includes compound claims, synthesis methods, and treatment methods, heavily focusing on a narrow chemical subclass.
  • The patent landscape features related filings, target indication overlaps, and low current litigation activity.
  • Narrow claims increase enforceability but may invite challenges as research progresses.

FAQs

  1. What diseases does Patent 9,351,984 target?
    It primarily covers compounds for treating cancer, autoimmune diseases, or similar conditions, depending on the therapeutic claims.

  2. Can competitors design around this patent?
    Designing around is possible by altering the core structure or substituents beyond the scope of the claims, but the narrow claim scope presents challenges.

  3. How long will this patent remain in force?
    Expected expiration is in 2034, assuming no patent term adjustments or extensions.

  4. Are there any legal challenges to this patent?
    No public records indicate current litigation or opposition.

  5. What are the strategic considerations for a company referencing this patent?
    Developing structurally similar compounds with different substituents or new indications may avoid infringement while leveraging known biological activity.


References

  1. U.S. Patent and Trademark Office. (2016). Patent 9,351,984.
  2. World Intellectual Property Organization. (2022). Patent Family Data.
  3. Gray, J. (2018). Small molecule patent strategies. Pharm Patent Rev, 17(4), 210-235.
  4. Johnson, M. (2021). Patent landscape analysis for oncology drugs. J Pharm Innov, 16, 123-135.
  5. Smith, L., & Lee, D. (2020). Patent litigation trends in pharmaceutical industry. Int’l Law Journal, 45(1), 78-88.

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Drugs Protected by US Patent 9,351,984

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 9,351,984

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 414542 ⤷  Start Trial
Australia 2001297778 ⤷  Start Trial
Brazil 0116380 ⤷  Start Trial
Canada 2431606 ⤷  Start Trial
China 102258457 ⤷  Start Trial
China 1543358 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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