Last Updated: September 24, 2026

Details for Patent: 8,912,187


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Summary for Patent: 8,912,187
Title:Phthalazinone derivatives
Abstract:Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NRX or CRXRY; if X═NRX then n is 1 or 2 and if X═CRXRY then n is 1; RX is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; RY is selected from H, hydroxy, amino; or RX and RY may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are both hydrogen, or when X is CRXRY, RC1, RC2, RX and RY, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R1 is selected from H and halo.
Inventor(s):Niall Morrison Barr Martin, Graeme Cameron Smith, Stephen Philip Jackson, Vincent Junior M Loh, Xiao-Ling Fan Cockcroft, Ian Timothy Williams Matthews, Keith Allan Menear, Frank Kerrigan, Alan Ashworth
Assignee: Kudos Pharmaceuticals Ltd
Application Number:US13/179,353
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 8,912,187

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,912,187

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom0305681.9Mar 12, 2003

International Family Members for US Patent 8,912,187

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1633724 ⤷  Start Trial C300726 Netherlands ⤷  Start Trial
European Patent Office 1633724 ⤷  Start Trial CR 2015 00012 Denmark ⤷  Start Trial
European Patent Office 1633724 ⤷  Start Trial C20150012 00136 Estonia ⤷  Start Trial
European Patent Office 1633724 ⤷  Start Trial 92680 Luxembourg ⤷  Start Trial
European Patent Office 1633724 ⤷  Start Trial PA2015016 Lithuania ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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