Last Updated: November 13, 2026

Details for Patent: 8,546,608

Name: Drug Patent Intelligence for US Patent 8546608
Creator: DrugPatentWatch
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Summary for Patent: 8,546,608

Title:	Proteasome inhibitors and methods of using the same
Abstract:	The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.
Inventor(s):	Raffaella Bernardini, Alberto Bernareggi, Paolo G. Cassara, Sankar Chatterjee, Germano D'Arasmo, Sergio De Munari, Edmondo Ferretti, Mohamed Iqbal, Ernesto Menta, Patricia A. Messina McLaughlin, Ambrogio Oliva
Assignee:	Takeda Pharmaceutical Co Ltd , Cephalon LLC
Application Number:	US13/249,738
Patent Claim Types: see list of patent claims	Compound;

Drugs Protected by US Patent 8,546,608

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Argentina	045381	⤷ Start Trial
Argentina	095249	⤷ Start Trial
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Australia	2004268946	⤷ Start Trial
Brazil	PI0413582	⤷ Start Trial
Canada	2535686	⤷ Start Trial
China	102603781	⤷ Start Trial
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