Details for Patent: 8,529,882
Summary for Patent: 8,529,882
| Title: | Peptidomimetic protease inhibitors |
| Abstract: | The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel stereoselective processes to intermediates. The invention is also directed to pharmaceutical compositions and to methods for using the compounds for inhibiting HCV protease or treating a patient suffering from an HCV infection or physiological condition related to the infection. Also provided are pharmaceutical combinations comprising, in addition to one or more HCV serine protease inhibitors, one or more interferons exhibiting anti-HCV activity and/or one or more compounds having anti HCV activity and a pharmaceutically acceptable carrier, and methods for treating or preventing a HCV infection in a patient using the compositions. The present invention is also directed to a kit or pharmaceutical pack for treating or preventing HCV infection in a patient. |
| Inventor(s): | Robert Edward Babine, Shu Hui Chen, Ivan Collado, Cristina Garcia-Paredes, John Irvin Glass, Ling Jin, Jason Eric Lamar, Raymond Samuel Parker, III, Nancy June Snyder, Xicheng David Sun, Deqi Guo, Yvonne Yee Mai Yip, Q. May Wang, Frantz Victor, Mark Joseph Tebbe, Robert B. Perni, Luc Farmer |
| Assignee: | Vertex Pharmaceuticals Inc |
| Application Number: | US13/541,436 |
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Patent Claim Types: see list of patent claims | Use; Composition; |
Drugs Protected by US Patent 8,529,882
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 8,529,882
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| European Patent Office | 1320540 | ⤷ Start Trial | C300518 | Netherlands | ⤷ Start Trial |
| European Patent Office | 1320540 | ⤷ Start Trial | PA2012003,C1320540 | Lithuania | ⤷ Start Trial |
| European Patent Office | 1320540 | ⤷ Start Trial | PA2012003 | Lithuania | ⤷ Start Trial |
| European Patent Office | 1320540 | ⤷ Start Trial | CA 2012 00007 | Denmark | ⤷ Start Trial |
| European Patent Office | 1320540 | ⤷ Start Trial | 91960 | Luxembourg | ⤷ Start Trial |
| European Patent Office | 1320540 | ⤷ Start Trial | 1290007-2 | Sweden | ⤷ Start Trial |
| European Patent Office | 1320540 | ⤷ Start Trial | 12C0018 | France | ⤷ Start Trial |
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
