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Serving hundreds of leading biopharmaceutical companies globally:

Medtronic
Mallinckrodt
Cerilliant
Chinese Patent Office
Healthtrust
Johnson and Johnson
Teva
Fuji
Moodys

Generated: May 26, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,529,882

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Which drugs does patent 8,529,882 protect, and when does it expire?

Patent 8,529,882 protects INCIVEK and is included in one NDA.

This patent has one hundred patent family members in thirty-five countries.

This patent has expired prematurely due to non-payment of maintenance fees. See details below.
Summary for Patent: 8,529,882
Title:Peptidomimetic protease inhibitors
Abstract: The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel stereoselective processes to intermediates. The invention is also directed to pharmaceutical compositions and to methods for using the compounds for inhibiting HCV protease or treating a patient suffering from an HCV infection or physiological condition related to the infection. Also provided are pharmaceutical combinations comprising, in addition to one or more HCV serine protease inhibitors, one or more interferons exhibiting anti-HCV activity and/or one or more compounds having anti HCV activity and a pharmaceutically acceptable carrier, and methods for treating or preventing a HCV infection in a patient using the compositions. The present invention is also directed to a kit or pharmaceutical pack for treating or preventing HCV infection in a patient.
Inventor(s): Babine; Robert Edward (Franklin, MA), Chen; Shu Hui (Carmel, IN), Collado; Ivan (Madrid, ES), Garcia-Paredes; Cristina (Madrid, ES), Glass; John Irvin (Indianapolis, IN), Jin; Ling (Carmel, IN), Lamar; Jason Eric (Indianapolis, IN), Parker, III; Raymond Samuel (Doylestown, PA), Snyder; Nancy June (Lizton, IN), Sun; Xicheng David (Superior, CO), Guo; Deqi (Carmel, IN), Yip; Yvonne Yee Mai (Indianapolis, IN), Wang; Q. May (Indianapolis, IN), Victor; Frantz (Indianapolis, IN), Tebbe; Mark Joseph (Hamburg, DE), Perni; Robert B. (Marlborough, MA), Farmer; Luc (Montreal, CA)
Assignee: Vertex Pharmaceuticals Incorporated (Cambridge, MA)
Application Number:13/541,436
Patent Claim Types:
see list of patent claims
Use; Composition;

Drugs Protected by US Patent 8,529,882

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Vertex Pharms INCIVEK telaprevir TABLET;ORAL 201917-001 May 23, 2011 DISCN No No ➤ Sign Up ➤ Sign Up METHOD OF TREATING CHRONIC HEPATITIS C ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 8,529,882

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
7,820,671 Peptidomimetic protease inhibitors ➤ Sign Up
8,252,923 Peptidomimetic protease inhibitors ➤ Sign Up
Patent No. Title Estimated Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
Baxter
Covington
Colorcon
Fish and Richardson
Moodys
Farmers Insurance
Queensland Health
US Department of Justice

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