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Last Updated: December 3, 2022

Details for Patent: 8,501,758


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Summary for Patent: 8,501,758
Title:Compounds and compositions as protein kinase inhibitors
Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
Inventor(s): Huang; Shenlin (San Diego, CA), Jin; Xianming (San Ramon, CA), Liu; Zuosheng (San Diego, CA), Poon; Daniel (Piedmont, CA), Tellew; John (La Jolla, CA), Wan; Yongqin (San Diego, CA), Wang; Xing (San Diego, CA), Xie; Yongping (San Diego, CA)
Assignee: IRM LLC (Hamilton, BM) Novartis AG (Basel, CH)
Application Number:12/870,130
Patent Claim Types:
see list of patent claims
Composition; Compound;

Drugs Protected by US Patent 8,501,758

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Array Biopharma Inc BRAFTOVI encorafenib CAPSULE;ORAL 210496-001 Jun 27, 2018 DISCN Yes No See Plans and Pricing See Plans and Pricing Y Y See Plans and Pricing
Array Biopharma Inc BRAFTOVI encorafenib CAPSULE;ORAL 210496-002 Jun 27, 2018 RX Yes Yes See Plans and Pricing See Plans and Pricing Y Y See Plans and Pricing
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,501,758

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 077975 See Plans and Pricing
Australia 2010286569 See Plans and Pricing
Brazil 112012004453 See Plans and Pricing
Canada 2771775 See Plans and Pricing
Chile 2012000340 See Plans and Pricing
China 102725283 See Plans and Pricing
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Harvard Business School
Express Scripts
Colorcon
Dow
Johnson and Johnson

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