Details for Patent: 8,501,158
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Summary for Patent: 8,501,158
Title: | Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents |
Abstract: | Pharmacological compositions, and methods for administration, of the type employing an iron oxide complex with a polyol or polyether. The methods of administration may comprise parenteral administration of an effective dose of the complex formulated in a biocompatible liquid delivered at a rate of from about 1 mL/sec to less than 1 mL/min and wherein upon administration the complex provides minimal detectable free iron in a subject, and minimal incidence of anaphylaxis. The pharmacological compositions are of the type employing a polyol or polyether iron oxide complex, which, upon parenteral administration to a subject, are substantially immunosilent, provide minimal anaphylaxis and minimal free iron, and undergo minimal dissolution in vivo. |
Inventor(s): | Groman; Ernest V. (Brookline, MA), Paul; Kenneth G. (Holliston, MA), Frigo; Timothy B. (Waltham, MA), Bengele; Howard (Canton, MA), Lewis; Jerome M. (Mewton, MA) |
Assignee: | AMAG Pharmaceuticals, Inc. (Lexington, MA) |
Application Number: | 12/963,308 |
Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 8,501,158 |
Patent Claim Types: see list of patent claims | Use; Composition; |
Drugs Protected by US Patent 8,501,158
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 8,501,158
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Austria | 446108 | ⤷ Try a Trial | |||
Cyprus | 1109527 | ⤷ Try a Trial | |||
Germany | 60043188 | ⤷ Try a Trial | |||
Denmark | 1169062 | ⤷ Try a Trial | |||
European Patent Office | 1169062 | ⤷ Try a Trial | C300558 | Netherlands | ⤷ Try a Trial |
European Patent Office | 1169062 | ⤷ Try a Trial | CA 2012 00050 | Denmark | ⤷ Try a Trial |
European Patent Office | 1169062 | ⤷ Try a Trial | 92114 | Luxembourg | ⤷ Try a Trial |
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |