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Last Updated: March 30, 2024

Details for Patent: 8,501,158


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Summary for Patent: 8,501,158
Title:Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents
Abstract: Pharmacological compositions, and methods for administration, of the type employing an iron oxide complex with a polyol or polyether. The methods of administration may comprise parenteral administration of an effective dose of the complex formulated in a biocompatible liquid delivered at a rate of from about 1 mL/sec to less than 1 mL/min and wherein upon administration the complex provides minimal detectable free iron in a subject, and minimal incidence of anaphylaxis. The pharmacological compositions are of the type employing a polyol or polyether iron oxide complex, which, upon parenteral administration to a subject, are substantially immunosilent, provide minimal anaphylaxis and minimal free iron, and undergo minimal dissolution in vivo.
Inventor(s): Groman; Ernest V. (Brookline, MA), Paul; Kenneth G. (Holliston, MA), Frigo; Timothy B. (Waltham, MA), Bengele; Howard (Canton, MA), Lewis; Jerome M. (Mewton, MA)
Assignee: AMAG Pharmaceuticals, Inc. (Lexington, MA)
Application Number:12/963,308
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 8,501,158
Patent Claim Types:
see list of patent claims
Use; Composition;

Drugs Protected by US Patent 8,501,158

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,501,158

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 446108 ⤷  Try a Trial
Cyprus 1109527 ⤷  Try a Trial
Germany 60043188 ⤷  Try a Trial
Denmark 1169062 ⤷  Try a Trial
European Patent Office 1169062 ⤷  Try a Trial C300558 Netherlands ⤷  Try a Trial
European Patent Office 1169062 ⤷  Try a Trial CA 2012 00050 Denmark ⤷  Try a Trial
European Patent Office 1169062 ⤷  Try a Trial 92114 Luxembourg ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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