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Serving hundreds of leading biopharmaceutical companies globally:

Daiichi Sankyo
Queensland Health
Julphar
Cerilliant
Johnson and Johnson
Cantor Fitzgerald
Argus Health
Federal Trade Commission
Merck

Generated: May 26, 2018

DrugPatentWatch Database Preview

Details for Patent: 7,820,660

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Which drugs does patent 7,820,660 protect, and when does it expire?

Patent 7,820,660 protects DUTREBIS and is included in one NDA.

This patent has forty-two patent family members in thirty-two countries.
Summary for Patent: 7,820,660
Title:N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase
Abstract: N-substituted 5-hydroxypyrimidin-6-one-4-carboxamides of formula: ##STR00001## are described as inhibitors of HIV integrase and inhibitors of HIV replication, wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are defined herein. These compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of preventing, treating or delaying the onset of AIDS and methods of preventing or treating infection by HIV are also described.
Inventor(s): Crescenzi; Benedetta (Rome, IT), Gardelli; Cristina (Ariccia, IT), Muraglia; Ester (Rome, IT), Nizi; Emanuela (Siena, IT), Orvieto; Federica (Rome, IT), Pace; Paola (Rome, IT), Pescatore; Giovanna (Cosenza, IT), Petrocchi; Alessia (Rome, IT), Poma; Marco (Grosseto, IT), Rowley; Michael (Axa, IT), Scarpelli; Rita (Rome, IT), Summa; Vincenzo (Velletri, IT)
Assignee: Instituto di Ricerche di Biologia Molecolare P. Angeletti S.p.A. (Rome, IT)
Application Number:12/214,595
Patent Claim Types:
see list of patent claims
Compound;

Drugs Protected by US Patent 7,820,660

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Merck Sharp Dohme DUTREBIS lamivudine; raltegravir potassium TABLET;ORAL 206510-001 Feb 6, 2015 DISCN No No ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 7,820,660

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
7,435,734 N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase ➤ Sign Up
7,169,780 N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase ➤ Sign Up
7,217,713 N-substituted hydroxypyrimidinone carboxamide inhibitors of HIV integrase ➤ Sign Up
Patent No. Title Estimated Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Accenture
Dow
Harvard Business School
Fuji
US Army
Colorcon
Julphar
Cerilliant
Daiichi Sankyo

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