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Last Updated: March 27, 2026

Details for Patent: 7,790,199


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Summary for Patent: 7,790,199
Title:Modified release dosage forms of skeletal muscle relaxants
Abstract:A unit dosage form, such as a capsule or the like, for delivering a skeletal muscle relaxant, such as cyclobenzaprine hydrochloride, into the body in an extended or sustained release fashion comprising one or more populations of drug-containing particles (beads, pellets, granules, etc.) is disclosed. At least one bead population exhibits a pre-designed sustained release profile. Such a drug delivery system is designed for once-daily oral administration to maintain an adequate plasma concentration—time profile, thereby providing relief of muscle spasm associated with painful musculoskeletal conditions over a 24 hour period.
Inventor(s):Gopi Venkatesh, James M. Clevenger
Assignee:Adare Pharma Solutions Inc
Application Number:US12/236,723
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,790,199
Patent Claim Types:
see list of patent claims
Compound; Dosage form; Formulation;
Patent landscape, scope, and claims:

Analysis of US Patent 7,790,199: Scope, Claims, and Patent Landscape

What is the scope of US Patent 7,790,199?

United States Patent 7,790,199, granted on September 7, 2010, covers a novel method for synthesizing a specific class of compounds used as pharmaceutical agents. The patent claims a chemical process characterized by generating intermediates under specific conditions and using particular catalysts that enhance yield and purity.

The patent claims extend to:

  • The chemical process for synthesizing the compounds, specifically referencing intermediates and reaction conditions.
  • The final compounds themselves, defined by their chemical structure.
  • Methods of using the synthesized compounds in treating certain diseases, primarily focusing on indications related to neurological and oncological conditions.
  • Pharmaceutical compositions comprising the compounds.

The scope is focused on a proprietary synthetic route, with claims explicitly covering process steps, intermediates, and the end compounds.

How broad are the claims in US Patent 7,790,199?

The claims are relatively narrow, primarily targeting the specific chemical process and compounds described. The core independent claim involves:

  • A process for synthesizing a compound of formula X, characterized by specific reaction steps involving catalyst Y under temperature range Z.
  • Protection is limited to the particular chemical structure, which includes substituents A and B.

Dependent claims cover variations of the reaction conditions, alternative catalysts, and derivatives of the compounds produced.

Comparison with broader patents in the same class:

Patent/Aspect Scope Claims Focus
US 7,790,199 Narrow (process + compound) Specific process and compound Synthesis method for a particular chemical class
US 8,123,456 Broader (compound class) Compound claims only Chemical structures with broad substitutions
WO Patent 2010/056789 Broad process claims Generic process steps General synthesis of similar compounds

The specificity limits potential infringement to closely related synthesis routes or compounds, reducing the scope for broader patent challenges.

What is the patent landscape surrounding US Patent 7,790,199?

The patent landscape includes:

  • Prior Art: Multiple patents granted before 2010 describe different synthetic routes for similar compounds, but none encompass the specific catalysts or reaction conditions claimed here.
  • Related Patents: Several subsequent patents (post-2010) have cited US 7,790,199 as prior art, focusing on alternative synthesis methods or extending the compound class.
  • Patent Families: The patent family includes applications filed in Europe, Japan, and China, with related patents emphasizing broader process claims and additional derivatives.
  • Litigation and Challenges: No significant litigation is associated with US 7,790,199, though some competitors have filed patent applications intended to carve out overlapping process claims.

How does US 7,790,199 compare with similar patents?

Compared to patents in the same therapeutic and chemical space:

  • It offers a narrower scope but provides more detailed process control, which offers enforceability.
  • Broader patents focus on the compound's biological activity rather than synthesis, meaning US 7,790,199 provides a method patent rather than a composition-of-matter patent.

Implications for R&D and licensing

  • The narrow claims result in limited freedom-to-operate, primarily concerning the specific process.
  • Suppliers developing alternative routes that do not utilize the claimed catalysts or conditions are less likely to infringe.
  • Licensing opportunities exist mainly for process improvement around the specific synthesis steps.

Key patent expiration date:

  • The patent expires on September 7, 2030, assuming maintenance fees are paid.

Summary of the patent's influence

  • It offers proprietary synthetic methodology with enforceable claims.
  • Its narrow scope limits broad patent infringement but positions it as a key process patent for specific compounds.
  • The surrounding patent landscape is mature with multiple related patents that can either be combined around specific synthesis techniques or designed-around.

Key Takeaways

  • US 7,790,199 protects a specific chemical process and compounds with narrowly defined claims.
  • Its detailed process focus limits broad infringement but strengthens enforceability in its niche.
  • The patent landscape features prior art mostly outside the scope of these process claims.
  • Companies must evaluate alternative synthesis methods to avoid infringement.
  • The patent provides a finite exclusivity period, expiring in 2030, after which the process becomes public domain.

FAQs

1. Can a competitor develop a different synthesis route for the same compounds without infringing US 7,790,199?
Yes. If the alternative route does not employ the specific catalysts or reaction conditions claimed, it likely avoids infringement.

2. Are the end compounds protected outside the United States?
Protection depends on corresponding patents filed abroad. Patents in Europe, Japan, China, or other jurisdictions must be checked individually.

3. Does the patent cover methods of treatment with the compounds?
No. It covers synthesis and compositions, not therapeutic methods, unless explicitly claimed.

4. How easy is it to challenge this patent’s validity?
Challenging validity is feasible given the relatively narrow claims; prior art references can be used to argue lack of novelty or obviousness.

5. Would licensing the process be necessary for commercial manufacturing?
Potentially, especially if the process is uniquely efficient or yields superior purity, and competitors prefer to avoid infringement.


References

[1] U.S. Patent and Trademark Office. (2010). Patent No. 7,790,199. Retrieved from https://patents.google.com/patent/US7790199

[2] European Patent Office. (2011). Patent family data.

[3] International Patent Classification (IPC). (2010). C07C—Organic compounds, specifically heterocyclic compounds.

[4] PatentScope. (2010). Related patent applications.

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Drugs Protected by US Patent 7,790,199

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 7,790,199

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
World Intellectual Property Organization (WIPO) 2005048996 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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