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Serving 500+ biopharmaceutical companies globally:

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Generated: July 23, 2017

DrugPatentWatch Database Preview

Details for Patent: 7,402,588

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Summary for Patent: 7,402,588

Title:Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane
Abstract:A method and composition for the treatment of HIV and HBV infections in humans is disclosed that includes administering an effective amount of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane, a pharmaceutically acceptable derivative thereof, including a 5' or N.sup.4 alkylated or acylated derivative, or a pharmaceutically acceptable salt thereof, in a pharmaceutically acceptable carrier.A process for the resolution of a racemic mixture of nucleoside enantiomers is also disclosed that includes the step of exposing the racemic mixture to an enzyme that preferentially catalyzes a reaction in one of the enantiomers.
Inventor(s): Liotta; Dennis C. (Stone Mountain, GA), Schinazi; Raymond F. (Decatur, GA), Choi; Woo-Baeg (North Brunswick, NJ)
Assignee: Emory University (Atlanta, GA)
Application Number:11/390,861
Patent Claim Types:
see list of patent claims
Use; Dosage form; Delivery; Composition; Compound;

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Serving 500+ biopharmaceutical companies globally:

Baxter
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Mallinckrodt
Express Scripts
Cerilliant
Johnson and Johnson
Cipla
Fuji
Healthtrust
Moodys

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