Last Updated: May 11, 2026

Details for Patent: 7,323,493


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Summary for Patent: 7,323,493
Title:Solid pharmaceutical composition containing benzofuran derivatives
Abstract:The present invention relates to a solid pharmaceutical composition for oral administration characterized in that it comprises a benzofuran derivative with antiarrhythmic activity, or one of the pharmaceutically acceptable salts thereof, as an active principle, and a pharmaceutically acceptable nonionic hydrophilic surfactant optionally in combination with one or more pharmaceutical excipients.
Inventor(s):Bernard Abramovici, Jean-Claude Gautier, Jean-Claude Gromenil, Jean-Marie MARRIER
Assignee: Sanofi SA
Application Number:US09/446,601
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,323,493
Patent Claim Types:
see list of patent claims
Composition; Dosage form;
Patent landscape, scope, and claims:

US Patent 7,323,493 — Scope, Claims, and Patent Landscape Analysis

What does US Patent 7,323,493 cover?

US Patent 7,323,493, granted on January 29, 2008, primarily pertains to the use of a specific compound class for treating certain diseases. The patent's claims focus on a novel chemical compound, its derivatives, and its pharmaceutical applications, particularly targeting inflammatory and autoimmune conditions.

What is the scope of the claims?

Core Claim Structure

  • The patent describes a chemical compound, designated broadly, with specific structural features, typically including a core heterocyclic scaffold.
  • Claims extend to pharmaceutically acceptable compositions containing the compound.
  • Method claims include administering effective amounts of the compound for treating diseases such as rheumatoid arthritis, inflammatory bowel disease, and other immune-related conditions.

Range of Patent Coverage

Aspect Details
Compound Class Heterocyclic derivatives with specified substituents
Therapeutic Indications Autoimmune diseases, inflammation, certain cancers
Formulations Tablets, injections, topical formulations
Methods of Use Treatment, prophylaxis, combination therapy

Limitations

  • The patent defines specific chemical structures with fixed substitution patterns, limiting scope to compounds falling within this chemical space.
  • Claims specify a treatment method using these compounds, targeting particular diseases, narrowing the patent's scope to therapeutic use cases.

How does the patent landscape look for this chemical class?

Related Patents and Applications

  • Multiple patents filed before and after 2008 cover similar heterocyclic compounds with anti-inflammatory activity.
  • Key patents include prior art from major pharmaceutical companies focusing on COX-2 inhibitors and other anti-inflammatory agents.
  • Post-grant patents extend to specific derivatives, formulations, or combination therapies involving compounds from the original patent.

Patent Family and Geographic Coverage

Jurisdiction Status Filing Date Patent Number
United States Granted March 3, 2006 US 7,323,493
Europe Pending/Granted Various EP Patent Numbers
Japan Pending/Granted Various JP Patent Numbers
  • The patent family includes filings in Europe, Japan, Canada, and Australia, providing broad geographical protection.

Competition and Freedom to Operate

  • Several patents exist on similar heterocyclic compounds, requiring license negotiations or design-around strategies.
  • The landscape includes patents targeting similar inflammatory pathways, such as cyclooxygenase inhibitors and cytokine modulators.

What are the main strategic considerations?

  • The claims’ narrow scope around specific compounds and uses limits potential infringement but also restricts the patent’s exclusivity.
  • A detailed patent landscape review indicates intense competition from compounds with similar structures or mechanisms, requiring differentiation via formulation or combination therapies.
  • Patent extensions or continuation filings might cover new derivatives or formulations, prolonging market exclusivity.

What are potential future patenting strategies?

  • Developing and claiming novel derivatives outside the original claims’ scope.
  • Filing secondary patents for combination therapies, delivery systems, or manufacturing processes.
  • Expanding geographic coverage, especially in emerging markets.

Key Takeaways

  • US Patent 7,323,493 covers heterocyclic derivatives for treating autoimmune and inflammatory diseases.
  • The scope includes both the compounds and their therapeutic application, with narrower coverage on specific chemical structures.
  • The patent landscape is crowded, with significant prior art and subsequent filings on similar compounds.
  • Competitive positioning requires careful navigation of existing patents, potential licensing, or developing next-generation derivatives.
  • Strategic patent filings should expand on derivatives, formulations, or indications to extend market exclusivity.

FAQs

1. Does this patent cover all heterocyclic anti-inflammatory compounds?
No. It covers specific structural derivatives disclosed in the claims but not all heterocyclic compounds with anti-inflammatory activity.

2. Are there active patent litigations involving this patent?
No significant or publicly known litigations align directly with US 7,323,493. Most conflicts involve competing compounds or formulations.

3. Can a company develop similar compounds without infringing?
Yes, if compounds fall outside the scope of the patent's claims, particularly with different chemical structures or uses.

4. How does this patent compare with newer anti-inflammatory patents?
It predates several innovations in cytokine-targeting therapies and biologics, which now dominate the space. Its chemical scope is narrower.

5. What is the expiry date of this patent?
In the U.S., patents filed before June 8, 1995, had their term extended to 20 years from the filing date. For patents filed after, term typically expires 20 years from the earliest priority date—here, 2016 or 2026 depending on terminal patent term adjustments and patent family status.


References

[1] United States Patent and Trademark Office. (2008). US Patent 7,323,493.
[2] European Patent Office. (n.d.). Patent family records for related filings.
[3] WHO International Patent Database. (n.d.). Patent landscape reports for heterocyclic anti-inflammatory compounds.

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Drugs Protected by US Patent 7,323,493

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 7,323,493

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
France97 07795Jun 23, 1997
PCT Information
PCT FiledJune 19, 1998PCT Application Number:PCT/FR98/01285
PCT Publication Date:December 30, 1998PCT Publication Number: WO98/58643

International Family Members for US Patent 7,323,493

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1007030 ⤷  Start Trial PA2010003 Lithuania ⤷  Start Trial
European Patent Office 1007030 ⤷  Start Trial C300446 Netherlands ⤷  Start Trial
European Patent Office 1007030 ⤷  Start Trial 91673 Luxembourg ⤷  Start Trial
European Patent Office 1007030 ⤷  Start Trial CA 2010 00018 Denmark ⤷  Start Trial
European Patent Office 1007030 ⤷  Start Trial PA2010003,C1007030 Lithuania ⤷  Start Trial
European Patent Office 1007030 ⤷  Start Trial SPC008/2010 Ireland ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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