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Generated: August 16, 2017

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Title:Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor
Abstract:In accordance with the present invention, there are provided methods to modulate processes mediated by retinoid receptors, employing high affinity, high specificity ligands for such receptors. In one aspect of the present invention, there are provided ligands which are more selective for the retinoid X receptor than is retinoic acid (i.e., rexoids). In another aspect of the present invention, alternative ligands (other than retinoic acid) have been discovered which are capable of inducing retinoic acid receptor mediated processes. In yet another aspect, methods have been developed for the preparation of such retinoid receptor ligands from readily available compounds.
Inventor(s): Evans; Ronald M. (La Jolla, CA), Mangelsdorf; David J. (Duncanville, TX), Heyman; Richard A. (Encinitas, CA), Boehm; Marcus F. (San Diego, CA), Eichele; Gregor (Houston, TX), Thaller; Christina (Houston, TX)
Assignee: The Salk Institute for Biological Studies (La Jolla, CA) Baylor College of Medicine (Waco, TX) Ligand Pharmaceuticals, Inc. (San Diego, CA)
Application Number:10/458,880
Patent Claim Types:
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Composition; Dosage form;

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International Patent Family for Patent: ► Subscribe

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office0807624► Subscribe
European Patent Office0617614► SubscribeCA 2001 00012Denmark► Subscribe
European Patent Office0617614► SubscribeSPC/GB01/014United Kingdom► Subscribe
European Patent Office0617614► SubscribeC300043Netherlands► Subscribe
European Patent Office0617614► Subscribe2001/009Ireland► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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