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Last Updated: May 30, 2023

Details for Patent: 6,992,218

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Summary for Patent: 6,992,218
Title:Method for obtaining aqueous formulations of oxidation-sensitive active principles
Abstract:A method for obtaining aqueous formulations with easily oxidizable active principles, notably phenols, stable over a prolonged period, comprising subjecting them to extreme deoxygenation by bubbling with an inert gas and/or placing wider vaccum, protecting them against possible resorption of oxygen by keeping them under an inert gas atmosphere, by filling, under inert gas, into bottles previously cleared of air by insufflation with inert gas, then subjecting them, while stoppering, to low pressure as obtained in the bottle, of 65,000 Pa maximum, to obtain aqueous solutions having a residual oxygen concentration in the solution below 2 ppm, and preferably of the order of 1 ppm and even 0.5 ppm useful as injectable preparations having an oxygen concentration in the solution below 2 ppm.
Inventor(s): Dietlin; Francois (La Vesinet, FR), Fredj; Daniele (Gif sur Yvette, FR)
Assignee: Pharmatop SCR (FR)
Application Number:10/332,060
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 6,992,218
Patent Claim Types:
see list of patent claims
Formulation; Process; Use;

Drugs Protected by US Patent 6,992,218

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 6,992,218

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
France00 07231Jun 06, 2000
France00 07231Jun 6, 2000
PCT Information
PCT FiledJune 06, 2001PCT Application Number:PCT/FR01/01749
PCT Publication Date:December 13, 2001PCT Publication Number: WO01/93830

International Family Members for US Patent 6,992,218

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
African Regional IP Organization (ARIPO) 1880 ⤷  Try a Trial
Australia 6612001 ⤷  Try a Trial
Canada 2415403 ⤷  Try a Trial
China 1556694 ⤷  Try a Trial
Czech Republic 200313 ⤷  Try a Trial
Algeria 3384 ⤷  Try a Trial
France 2809619 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

Express Scripts
Johnson and Johnson
Harvard Business School

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