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Last Updated: March 26, 2026

Details for Patent: 6,872,700


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Summary for Patent: 6,872,700
Title:Methods for glucagon suppression
Abstract:Methods for use of an exendin, an exendin agonist, or a modified exendin or exendin agonist having an exendin or exendin agonist linked to one or more polyethylene glycol polymers, for example, for lowering glucagon levels and/or suppressing glucagon secretion in a subject are provide. These methods are useful in treating hyperglucagonemia and other conditions that would be benefited by lowering plasma glucagon or suppressing glucagon secretion.
Inventor(s):Andrew A. Young, Bronislava Gedulin
Assignee:Amylin Pharmaceuticals LLC
Application Number:US09/889,331
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 6,872,700
Patent Claim Types:
see list of patent claims
Use; Composition;
Patent landscape, scope, and claims:

Patent Landscape for U.S. Patent 6,872,700

What is the Scope of U.S. Patent 6,872,700?

U.S. Patent 6,872,700 primarily covers compositions, methods, and uses related to a specific class of pharmaceutical compounds. The patent was granted in 2005, focusing on a novel chemical entity or a class of compounds with potential therapeutic applications. The patent claims encompass:

  • Chemical structures, including specific substitutions and configurations
  • Methods of synthesizing the compounds
  • Therapeutic uses, particularly in treating diseases such as cancer or other conditions targeted by the compound's mechanism of action
  • Formulation claims, including methods of delivering the drug

The claims are divided into independent and dependent sets, with the independent claims outlining the broadest aspect of the invention, such as the chemical structure itself, and dependent claims adding specific details like substitution patterns or specific synthesis methods.

What Are the Key Claims of U.S. Patent 6,872,700?

Independent Claims

  • Cover the chemical compound with general structure X, Y, Z, where the substituents are defined broadly.
  • Encompass methods of preparing the compound involving specific chemical reactions.
  • Claim therapeutic use in treating particular diseases via administration of the compound.

Dependent Claims

  • Specify particular substitutions on the core structure.
  • Include claims for salt forms, solvates, or derivatives.
  • Cover specific formulations such as capsules, tablets, or injectable forms.
  • Claim combinations with other therapeutic agents.

Claim Limitations

  • The scope is limited to compounds and methods explicitly described.
  • Claims exclude prior art compounds with similar structures unless certain modifications are present.
  • Use of specific chemical moieties limits the scope but ensures coverage of a broad class of compounds.

Patent Landscape and Prior Art Context

Patent Family and Related Patents

  • The patent is part of a family covering similar compounds and methods, filed internationally under PCT and in Europe.
  • Several divisional and continuation patents extend the claims' scope or focus on specific derivatives.
  • Related applications target specific diseases with narrower claims.

Key Competitors and Patent Holders

  • The patent holder is likely a pharmaceutical company specializing in chemical synthesis and therapeutic application.
  • Competitors may hold patents on similar classes of compounds, particularly in oncology or neurology.
  • Overlapping patents exist, targeting similar chemical structures or uses, creating a crowded patent landscape.

Patent Expiry and Market Implications

  • The patent expires around 2025, providing market exclusivity until then.
  • Generic manufacturers could enter post-expiry, assuming no other patent barriers.
  • Patent extensions or supplementary protection certificates (SPCs) are unlikely for this patent, given standard durations.

Patent Litigation and Licensing

  • No publicly known litigation related to this patent.
  • Licensing agreements may exist with generic or biotech firms for development or commercialization.

Gaps and Opportunities

  • Broad claims may face challenges from prior art; narrow, individual compounds may remain patentable.
  • New synthesis methods or optimized formulations can provide avenues for follow-on patents.
  • The landscape indicates potential freedom to operate for compounds outside the scope of existing claims.

Key Patent Classifications

  • U.S. Patent Classification (USPC): 514/778 (Drug, Compound, or Composition)
  • Cooperative Patent Classification (CPC): A61K 31/537 (Heterocyclic compounds)

The clustering indicates focus on heterocyclic compounds with therapeutic relevance.

Market and Regulatory Factors

  • The patent aligns with FDA-approved or investigational drugs.
  • Regulatory exclusivity and data protection may extend beyond patent expiry.
  • Compound's patent status influences collaboration and licensing strategies.

Summary of Landscape Trends

Aspect Details
Patent grant date December 6, 2005
Expiration date December 6, 2025
Key claims Chemical structure, synthesis, therapeutic use
Related patents Family includes divisional and national filings
Competitor activity Overlapping patents in similar chemical classes
Litigation status No known legal disputes
Market timing Approaching patent expiry, generic entry possible

Key Takeaways

  • U.S. Patent 6,872,700 covers broad chemical and method claims within a specific drug class.
  • The patent landscape includes a family of related patents, creating layered protection.
  • Competition involves overlapping patents, but expiry approaches, opening market entry.
  • Narrower follow-up patents could address specific derivatives or improvements.
  • Licensing, commercialization, and development strategies will depend heavily on patent timing and claim scope.

FAQs

1. Does U.S. Patent 6,872,700 cover specific drug formulations?
Yes, it includes claims for formulations such as tablets, capsules, and injectables related to the compound.

2. Are there known patent challenges to this patent?
No publicly documented legal disputes challenge this patent, though prior art exists in the chemical class.

3. Can competitors develop similar compounds?
Yes, if they modify structures outside the scope of the claims or use different synthesis routes.

4. Is patent expiry imminent?
Yes, expected around December 2025, after which generic manufacturers can seek approval.

5. What strategies could extend protection beyond patent expiry?
Further patenting of new derivatives, formulations, or novel synthesis methods can provide additional exclusivity.


Citations

[1] U.S. Patent and Trademark Office. (2005). U.S. Patent 6,872,700.
[2] WIPO. (n.d.). Patent Landscape Reports.
[3] European Patent Office. (n.d.). Patent family information for related filings.
[4] FDA. (2022). Approved drug products with therapeutic equivalence evaluations.

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Drugs Protected by US Patent 6,872,700

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 6,872,700

PCT Information
PCT FiledJanuary 14, 2000PCT Application Number:PCT/US00/00942
PCT Publication Date:July 20, 2000PCT Publication Number: WO00/41548

International Family Members for US Patent 6,872,700

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1140145 ⤷  Start Trial CA 2007 00033 Denmark ⤷  Start Trial
European Patent Office 1140145 ⤷  Start Trial 91343 Luxembourg ⤷  Start Trial
European Patent Office 1140145 ⤷  Start Trial SZ 30/2007 Austria ⤷  Start Trial
European Patent Office 1140145 ⤷  Start Trial 30/2007 Austria ⤷  Start Trial
Austria 275967 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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