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Last Updated: April 26, 2024

Details for Patent: 6,869,939


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Summary for Patent: 6,869,939
Title: Formulations containing amiodarone and sulfoalkyl ether cyclodextrin
Abstract:The present invention provides aqueous parenteral formulations containing an antiarrhythmic agent, such as amiodarone, and a sulfoalkyl ether cyclodextrin. The liquid formulations are clear, sterilizable, and chemically and physically stable. The liquid formulations do not require a surfactant and do not precipitate upon dilution with distilled water or other pharmaceutically acceptable liquid carrier. The sulfoalkyl ether cyclodextrin-containing formulation provides significant advantages over other cyclodextrin-containing formulations of amiodarone. The formulation can be prepared in acidic, neutral and slightly basic medium while providing acceptable concentrations of amiodarone suitable for parenteral administration. An SAE-CD-containing formulation of amiodarone can be provided in liquid form or as a reconstitutable powder. Moreover, highly concentrated solutions exceeding 200 mg of amiodarone per mL can be prepared. Solutions can be made either dilutable or non-dilutable with water at room temperature or under conditions typically encountered in the clinic.
Inventor(s): Mosher; Gerold L. (Kansas City, MO), Johnson; Karen T. (Lawrence, KS), Gayed; Atef A. (Overland Park, KS)
Assignee: CyDex, Inc. (Lenexa, KS)
Application Number:10/139,620
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 6,869,939
Patent Claim Types:
see list of patent claims
Formulation; Compound; Composition; Use;

Drugs Protected by US Patent 6,869,939

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 6,869,939

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 535239 ⤷  Try a Trial
Australia 2003234285 ⤷  Try a Trial
Canada 2483774 ⤷  Try a Trial
Cyprus 1112527 ⤷  Try a Trial
Denmark 1501496 ⤷  Try a Trial
Denmark 2402008 ⤷  Try a Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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